New vaccine design based on defective genomes that combines features of attenuated and inactivated vaccines.

New vaccine design based on defective genomes that combines features of attenuated and inactivated vaccines.

<h4>Background</h4>New vaccine designs are needed to control diseases associated with antigenically variable RNA viruses. Foot-and-mouth disease (FMD) is a highly contagious disease of livestock that inflicts severe economic losses. Although the current whole-virus chemically inactivated...

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Bibliographic Details
Main Authors: Teresa Rodríguez-Calvo, Samuel Ojosnegros, Marta Sanz-Ramos, Juan García-Arriaza, Cristina Escarmís, Esteban Domingo, Noemí Sevilla
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20454676/?tool=EBI

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