Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity.
The development of safe subunit vaccines requires adjuvants that augment immunogenicity of non-replicating protein-based antigens. Current vaccines against infectious diseases preferentially induce protective antibodies driven by adjuvants such as alum. However, the contribution of antibody to host...
Main Authors: | Lucas Dos Santos Dias, Hannah E Dobson, Brock Kingstad Bakke, Gregory C Kujoth, Junfeng Huang, Elaine M Kohn, Cleison Ledesma Taira, Huafeng Wang, Nitin T Supekar, J Scott Fites, Daisy Gates, Christina L Gomez, Charles A Specht, Stuart M Levitz, Parastoo Azadi, Lingjun Li, Marulasiddappa Suresh, Bruce S Klein, Marcel Wüthrich |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-03-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1009324 |
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