The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review
Malnutrition and muscle wasting are associated with impaired physical functioning and quality of life in oncology patients. Patients diagnosed with upper gastrointestinal (GI) cancers are considered at high risk of malnutrition and impaired function. Due to continuous improvement in upper GI cancer...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/13/8/2842 |
| _version_ | 1797522536064352256 |
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| author | Fatemeh Sadeghi David Mockler Emer M. Guinan Juliette Hussey Suzanne L. Doyle |
| author_facet | Fatemeh Sadeghi David Mockler Emer M. Guinan Juliette Hussey Suzanne L. Doyle |
| author_sort | Fatemeh Sadeghi |
| collection | DOAJ |
| description | Malnutrition and muscle wasting are associated with impaired physical functioning and quality of life in oncology patients. Patients diagnosed with upper gastrointestinal (GI) cancers are considered at high risk of malnutrition and impaired function. Due to continuous improvement in upper GI cancer survival rates, there has been an increased focus on multimodal interventions aimed at minimizing the adverse effects of cancer treatments and enhancing survivors’ quality of life. The present study aimed to evaluate the effectiveness of combined nutritional and exercise interventions in improving muscle wasting, physical functioning, and quality of life in patients with upper GI cancer. A comprehensive search was conducted in MEDLINE, EMBASE, Web of Science, Cochrane Library, and CINHAL. Of the 4780 identified articles, 148 were selected for full-text review, of which 5 studies met the inclusion criteria. Whilst reviewed studies showed promising effects of multimodal interventions on physical functioning, no significant differences in postoperative complications and hospital stay were observed. Limited available evidence showed conflicting results regarding the effectiveness of these interventions on preserving muscle mass and improving health-related quality of life. Further studies examining the impact of nutrition and exercise interventions on upper GI patient outcomes are required and would benefit from reporting a core outcome set. |
| first_indexed | 2024-03-10T08:30:48Z |
| format | Article |
| id | doaj.art-fc81da0098654b44856b0dc0e662bb2b |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T08:30:48Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-fc81da0098654b44856b0dc0e662bb2b2023-11-22T09:06:56ZengMDPI AGNutrients2072-66432021-08-01138284210.3390/nu13082842The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic ReviewFatemeh Sadeghi0David Mockler1Emer M. Guinan2Juliette Hussey3Suzanne L. Doyle4Discipline of Physiotherapy, Trinity College Dublin, D08 W9RT Dublin, IrelandJohn Stearne Medical Library, Trinity Centre for Health Sciences, D08 W9RT Dublin, IrelandTrinity College Dublin, School of Medicine, D02 R590 Dublin, IrelandDiscipline of Physiotherapy, Trinity College Dublin, D08 W9RT Dublin, IrelandSchool of Biological and Health Sciences, Technological University Dublin, Grangegorman, D07 XT95 Dublin, IrelandMalnutrition and muscle wasting are associated with impaired physical functioning and quality of life in oncology patients. Patients diagnosed with upper gastrointestinal (GI) cancers are considered at high risk of malnutrition and impaired function. Due to continuous improvement in upper GI cancer survival rates, there has been an increased focus on multimodal interventions aimed at minimizing the adverse effects of cancer treatments and enhancing survivors’ quality of life. The present study aimed to evaluate the effectiveness of combined nutritional and exercise interventions in improving muscle wasting, physical functioning, and quality of life in patients with upper GI cancer. A comprehensive search was conducted in MEDLINE, EMBASE, Web of Science, Cochrane Library, and CINHAL. Of the 4780 identified articles, 148 were selected for full-text review, of which 5 studies met the inclusion criteria. Whilst reviewed studies showed promising effects of multimodal interventions on physical functioning, no significant differences in postoperative complications and hospital stay were observed. Limited available evidence showed conflicting results regarding the effectiveness of these interventions on preserving muscle mass and improving health-related quality of life. Further studies examining the impact of nutrition and exercise interventions on upper GI patient outcomes are required and would benefit from reporting a core outcome set.https://www.mdpi.com/2072-6643/13/8/2842cancergastrointestinalnutritionexerciserehabilitationmultidisciplinary |
| spellingShingle | Fatemeh Sadeghi David Mockler Emer M. Guinan Juliette Hussey Suzanne L. Doyle The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review Nutrients cancer gastrointestinal nutrition exercise rehabilitation multidisciplinary |
| title | The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review |
| title_full | The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review |
| title_fullStr | The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review |
| title_full_unstemmed | The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review |
| title_short | The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review |
| title_sort | effectiveness of nutrition interventions combined with exercise in upper gastrointestinal cancers a systematic review |
| topic | cancer gastrointestinal nutrition exercise rehabilitation multidisciplinary |
| url | https://www.mdpi.com/2072-6643/13/8/2842 |
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