Association of dietary inflammatory index with chronic kidney disease and kidney stones in Iranian adults: A cross-sectional study within the Ravansar non-communicable diseases cohort
Chronic inflammation plays a central role in the pathogenesis of chronic kidney disease (CKD). The association of dietary inflammatory index (DII) with CKD remains underexplored. Thus, the present study aimed to determine the association between the DII, risk of CKD, and kidney stone formation using...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2022.955562/full |
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| author | Jalal Moludi Hawal Lateef Fateh Yahya Pasdar Mehdi Moradinazar Leila Sheikhi Amir Saber Negin Kamari Mitra Bonyani Farid Najafi Priyankar Dey |
| author_facet | Jalal Moludi Hawal Lateef Fateh Yahya Pasdar Mehdi Moradinazar Leila Sheikhi Amir Saber Negin Kamari Mitra Bonyani Farid Najafi Priyankar Dey |
| author_sort | Jalal Moludi |
| collection | DOAJ |
| description | Chronic inflammation plays a central role in the pathogenesis of chronic kidney disease (CKD). The association of dietary inflammatory index (DII) with CKD remains underexplored. Thus, the present study aimed to determine the association between the DII, risk of CKD, and kidney stone formation using the data from the Ravansar non-communicable diseases (RaNCD) cohort study conducted in Kermanshah, Iran. The cross-sectional study was conducted using the recruitment phase data of the RaNCD cohort study comprising 9,824 individuals with an age range of 35–65 years. Food frequency questionnaires (FFQ) were used to evaluate the association between diet and DII scores. Renal function was assessed using estimated glomerular filtration rate (eGFR), blood urea nitrogen (BUN), and serum creatinine (Cr) level. CKD was defined based on eGFR. The prevalence of kidney stones was evaluated by participants’ self-report. A total of 1,791 participants (18.24%) had kidney stones, while a majority were in the first quartile (27.69%). Out of 9,824 subjects, 1,747 subjects (eGFR: 18.50 ml/min per 1.73 m2; 95% CI: 17.72–19.30) had CKD. A significant trend for eGFR across all quartiles (Qs) of DII was observed. The odds ratio of CKD in the fourth quartile (pro-inflammatory diet) was 4.38-times higher than in the first quartile (anti-inflammatory diet) of DII (95% CI = 3.58–5.36). Women were found to be more likely to have less eGFR than men in the DII Qs. Collectively, the findings indicated that consumption of a pro-inflammatory diet was associated with a high occurrence of CKD. As a matter of interest, the results also revealed that a pro-inflammatory diet had no significant correlation with kidney stone development. |
| first_indexed | 2024-04-11T17:00:49Z |
| format | Article |
| id | doaj.art-fc8397960a9a45adafa0762d6274aea7 |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-04-11T17:00:49Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-fc8397960a9a45adafa0762d6274aea72022-12-22T04:13:09ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-10-01910.3389/fnut.2022.955562955562Association of dietary inflammatory index with chronic kidney disease and kidney stones in Iranian adults: A cross-sectional study within the Ravansar non-communicable diseases cohortJalal Moludi0Hawal Lateef Fateh1Yahya Pasdar2Mehdi Moradinazar3Leila Sheikhi4Amir Saber5Negin Kamari6Mitra Bonyani7Farid Najafi8Priyankar Dey9School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, IranDepartment of Nursing, Sulaimani Polytechnic University, Sulaimani, IraqSchool of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, IranBehavioral Disease Research Center, Kermanshah University of Medical Sciences, Kermanshah, IranDepartment of Nutrition, School of Allied Medical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranSchool of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, IranSchool of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, IranMedical Education Development Center, Kermanshah University of Medical Sciences, Kermanshah, IranResearch Center for Environmental Determinants of Health, Kermanshah University of Medical Sciences, Kermanshah, IranDepartment of Biotechnology, Thapar Institute of Engineering and Technology, Patiala, IndiaChronic inflammation plays a central role in the pathogenesis of chronic kidney disease (CKD). The association of dietary inflammatory index (DII) with CKD remains underexplored. Thus, the present study aimed to determine the association between the DII, risk of CKD, and kidney stone formation using the data from the Ravansar non-communicable diseases (RaNCD) cohort study conducted in Kermanshah, Iran. The cross-sectional study was conducted using the recruitment phase data of the RaNCD cohort study comprising 9,824 individuals with an age range of 35–65 years. Food frequency questionnaires (FFQ) were used to evaluate the association between diet and DII scores. Renal function was assessed using estimated glomerular filtration rate (eGFR), blood urea nitrogen (BUN), and serum creatinine (Cr) level. CKD was defined based on eGFR. The prevalence of kidney stones was evaluated by participants’ self-report. A total of 1,791 participants (18.24%) had kidney stones, while a majority were in the first quartile (27.69%). Out of 9,824 subjects, 1,747 subjects (eGFR: 18.50 ml/min per 1.73 m2; 95% CI: 17.72–19.30) had CKD. A significant trend for eGFR across all quartiles (Qs) of DII was observed. The odds ratio of CKD in the fourth quartile (pro-inflammatory diet) was 4.38-times higher than in the first quartile (anti-inflammatory diet) of DII (95% CI = 3.58–5.36). Women were found to be more likely to have less eGFR than men in the DII Qs. Collectively, the findings indicated that consumption of a pro-inflammatory diet was associated with a high occurrence of CKD. As a matter of interest, the results also revealed that a pro-inflammatory diet had no significant correlation with kidney stone development.https://www.frontiersin.org/articles/10.3389/fnut.2022.955562/fulldietary inflammatory indexchronic kidney diseaseglomerular filtration ratekidney stonescohort study |
| spellingShingle | Jalal Moludi Hawal Lateef Fateh Yahya Pasdar Mehdi Moradinazar Leila Sheikhi Amir Saber Negin Kamari Mitra Bonyani Farid Najafi Priyankar Dey Association of dietary inflammatory index with chronic kidney disease and kidney stones in Iranian adults: A cross-sectional study within the Ravansar non-communicable diseases cohort Frontiers in Nutrition dietary inflammatory index chronic kidney disease glomerular filtration rate kidney stones cohort study |
| title | Association of dietary inflammatory index with chronic kidney disease and kidney stones in Iranian adults: A cross-sectional study within the Ravansar non-communicable diseases cohort |
| title_full | Association of dietary inflammatory index with chronic kidney disease and kidney stones in Iranian adults: A cross-sectional study within the Ravansar non-communicable diseases cohort |
| title_fullStr | Association of dietary inflammatory index with chronic kidney disease and kidney stones in Iranian adults: A cross-sectional study within the Ravansar non-communicable diseases cohort |
| title_full_unstemmed | Association of dietary inflammatory index with chronic kidney disease and kidney stones in Iranian adults: A cross-sectional study within the Ravansar non-communicable diseases cohort |
| title_short | Association of dietary inflammatory index with chronic kidney disease and kidney stones in Iranian adults: A cross-sectional study within the Ravansar non-communicable diseases cohort |
| title_sort | association of dietary inflammatory index with chronic kidney disease and kidney stones in iranian adults a cross sectional study within the ravansar non communicable diseases cohort |
| topic | dietary inflammatory index chronic kidney disease glomerular filtration rate kidney stones cohort study |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2022.955562/full |
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