Predictive evolutionary modelling for influenza virus by site-based dynamics of mutations

Predictive evolutionary modelling for influenza virus by site-based dynamics of mutations

Abstract Influenza virus continuously evolves to escape human adaptive immunity and generates seasonal epidemics. Therefore, influenza vaccine strains need to be updated annually for the upcoming flu season to ensure vaccine effectiveness. We develop a computational approach, beth-1, to forecast vir...

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Bibliographic Details
Main Authors: Jingzhi Lou, Weiwen Liang, Lirong Cao, Inchi Hu, Shi Zhao, Zigui Chen, Renee Wan Yi Chan, Peter Pak Hang Cheung, Hong Zheng, Caiqi Liu, Qi Li, Marc Ka Chun Chong, Yexian Zhang, Eng-kiong Yeoh, Paul Kay-Sheung Chan, Benny Chung Ying Zee, Chris Ka Pun Mok, Maggie Haitian Wang
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46918-0

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