Expression of CETP and of splice variants induces the same level of ER stress despite secretion efficiency differences

Expression of CETP and of splice variants induces the same level of ER stress despite secretion efficiency differences

The cholesteryl ester transfer protein (CETP) gene has been associated with a variety of phenotypes, including HDL-cholesterol levels and, more sporadically, with cardiovascular disease, obesity, and extreme longevity. Alterations of CETP activity levels can be caused by single-base polymorphisms as...

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Bibliographic Details
Main Authors: Maruja E. Lira, A. Katrina Loomis, Sara A. Paciga, David B. Lloyd, John F. Thompson
Format: Article
Language:English
Published: Elsevier 2008-09-01
Series:Journal of Lipid Research
Subjects:
HDL-cholesterol
atherosclerosis
Alu sequence
endoplasmic reticulum
cholesteryl ester transfer protein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520346642

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