Contribution of Connexin Hemichannels to the Decreases in Cell Viability Induced by Linoleic Acid in the Human Lens Epithelial Cells (HLE-B3)

Contribution of Connexin Hemichannels to the Decreases in Cell Viability Induced by Linoleic Acid in the Human Lens Epithelial Cells (HLE-B3)

Connexin (Cx) proteins form gap junction channels (GJC) and hemichannels that a allow bidirectional flow of ions and metabolites between the cytoplasm and extracellular space, respectively. Under physiological conditions, hemichannels have a very low probability of opening, but in certain pathologie...

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Bibliographic Details
Main Authors: Vania A. Figueroa, Oscar Jara, Carolina A. Oliva, Marcelo Ezquer, Fernando Ezquer, Mauricio A. Retamal, Agustín D. Martínez, Guillermo A. Altenberg, Aníbal A. Vargas
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Physiology
Subjects:
lens
connexin
polyunsaturated fatty acids
cell death
hemichannels
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01574/full

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