Warthin’s Tumour: A Case Report and Review on Pathogenesis and its Histological Subtypes

Warthin’s tumour/ Papillary cystadenoma lymphomatosum (PCL) constitutes a minority of salivary gland neoplasms and it is a monomorphic adenoma which primarily involves the parotid gland. Warthin’s tumour shows multiple cysts that have numerous papillations covered by bilayered columnar and basaloid...

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Main Authors: Raghu A R, Shweta Rehani, Kundendu Arya Bishen, Shitalkumar Sagari
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2014-09-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/4908/8503_CE(Ra)_F(Sh)_PF1(SNAK)_PFA(Sh)_PF2(PAG).pdf
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author Raghu A R
Shweta Rehani
Kundendu Arya Bishen
Shitalkumar Sagari
author_facet Raghu A R
Shweta Rehani
Kundendu Arya Bishen
Shitalkumar Sagari
author_sort Raghu A R
collection DOAJ
description Warthin’s tumour/ Papillary cystadenoma lymphomatosum (PCL) constitutes a minority of salivary gland neoplasms and it is a monomorphic adenoma which primarily involves the parotid gland. Warthin’s tumour shows multiple cysts that have numerous papillations covered by bilayered columnar and basaloid oncocytic epithelium. The connective tissue portion shows proliferation of follicle- containing lymphoid tissue which necessitates careful distinction for diagnosis. Although, Warthin’s tumour presents as a clinically benign, slow-growing, usually asymptomatic lesion with low rates of recurrences and malignant transformation, but still this tumour is considered unique because of its histological appearance and unknown origin and pathogenesis. Here, we report a case of Warthin’s tumour of five years duration in a 50- year-old male patient in the right parotid gland and also review and discuss various concepts concerning the development of this tumour along with a comprehensive literature on its clinic-pathologic features.
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spelling doaj.art-fc880bf6bc0449d2adef1563c5da05812022-12-21T23:30:09ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-09-0189ZD37ZD4010.7860/JCDR/2014/8503.4908Warthin’s Tumour: A Case Report and Review on Pathogenesis and its Histological SubtypesRaghu A R0Shweta Rehani1Kundendu Arya Bishen2Shitalkumar Sagari3Professor, Department of Oral Pathology & Microbiology, Manipal College of Dental Sciences, Manipal, Karnataka, India.Reader, Department of Oral Pathology & Microbiology, Sudha Rustagi College of Dental Sciences and Research Institute, Faridabad, Haryana, India.Reader, Department of Oral Pathology & Microbiology, Jodhpur Dental College, Jodhpur, Rajasthan, India.Senior Lecturer, Department of Oral Pathology & Microbiology, Jodhpur Dental College, Jodhpur, Rajasthan, India.Warthin’s tumour/ Papillary cystadenoma lymphomatosum (PCL) constitutes a minority of salivary gland neoplasms and it is a monomorphic adenoma which primarily involves the parotid gland. Warthin’s tumour shows multiple cysts that have numerous papillations covered by bilayered columnar and basaloid oncocytic epithelium. The connective tissue portion shows proliferation of follicle- containing lymphoid tissue which necessitates careful distinction for diagnosis. Although, Warthin’s tumour presents as a clinically benign, slow-growing, usually asymptomatic lesion with low rates of recurrences and malignant transformation, but still this tumour is considered unique because of its histological appearance and unknown origin and pathogenesis. Here, we report a case of Warthin’s tumour of five years duration in a 50- year-old male patient in the right parotid gland and also review and discuss various concepts concerning the development of this tumour along with a comprehensive literature on its clinic-pathologic features.https://jcdr.net/articles/PDF/4908/8503_CE(Ra)_F(Sh)_PF1(SNAK)_PFA(Sh)_PF2(PAG).pdfdevelopmenthistogenesiswarthin’s tumor
spellingShingle Raghu A R
Shweta Rehani
Kundendu Arya Bishen
Shitalkumar Sagari
Warthin’s Tumour: A Case Report and Review on Pathogenesis and its Histological Subtypes
Journal of Clinical and Diagnostic Research
development
histogenesis
warthin’s tumor
title Warthin’s Tumour: A Case Report and Review on Pathogenesis and its Histological Subtypes
title_full Warthin’s Tumour: A Case Report and Review on Pathogenesis and its Histological Subtypes
title_fullStr Warthin’s Tumour: A Case Report and Review on Pathogenesis and its Histological Subtypes
title_full_unstemmed Warthin’s Tumour: A Case Report and Review on Pathogenesis and its Histological Subtypes
title_short Warthin’s Tumour: A Case Report and Review on Pathogenesis and its Histological Subtypes
title_sort warthin s tumour a case report and review on pathogenesis and its histological subtypes
topic development
histogenesis
warthin’s tumor
url https://jcdr.net/articles/PDF/4908/8503_CE(Ra)_F(Sh)_PF1(SNAK)_PFA(Sh)_PF2(PAG).pdf
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AT kundenduaryabishen warthinstumouracasereportandreviewonpathogenesisanditshistologicalsubtypes
AT shitalkumarsagari warthinstumouracasereportandreviewonpathogenesisanditshistologicalsubtypes