Advanced microfluidic devices for fabricating multi‐structural hydrogel microsphere
Abstract Hydrogel microspheres are a novel functional material, arousing much attention in various fields. Microfluidics, a technology that controls and manipulates fluids at the micron scale, has emerged as a promising method for fabricating hydrogel microspheres due to its ability to generate unif...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-12-01
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| Series: | Exploration |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/EXP.20210036 |
| _version_ | 1797832669012164608 |
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| author | Zehao Chen Zhendong Lv Zhen Zhang David A. Weitz Hongbo Zhang Yuhui Zhang Wenguo Cui |
| author_facet | Zehao Chen Zhendong Lv Zhen Zhang David A. Weitz Hongbo Zhang Yuhui Zhang Wenguo Cui |
| author_sort | Zehao Chen |
| collection | DOAJ |
| description | Abstract Hydrogel microspheres are a novel functional material, arousing much attention in various fields. Microfluidics, a technology that controls and manipulates fluids at the micron scale, has emerged as a promising method for fabricating hydrogel microspheres due to its ability to generate uniform microspheres with controlled geometry. With the development of microfluidic devices, more complicated hydrogel microspheres with multiple structures can be constructed. This review presents an overview of advances in microfluidics for designing and engineering hydrogel microspheres. It starts with an introduction to the features of hydrogel microspheres and microfluidic techniques, followed by a discussion of material selection for fabricating microfluidic devices. Then the progress of microfluidic devices for single‐component and composite hydrogel microspheres is described, and the method for optimizing microfluidic devices is also given. Finally, this review discusses the key research directions and applications of microfluidics for hydrogel microsphere in the future. |
| first_indexed | 2024-04-09T14:11:32Z |
| format | Article |
| id | doaj.art-fc8847bfa320420080cfeb073d288c56 |
| institution | Directory Open Access Journal |
| issn | 2766-8509 2766-2098 |
| language | English |
| last_indexed | 2024-04-09T14:11:32Z |
| publishDate | 2021-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Exploration |
| spelling | doaj.art-fc8847bfa320420080cfeb073d288c562023-05-06T11:00:46ZengWileyExploration2766-85092766-20982021-12-0113n/an/a10.1002/EXP.20210036Advanced microfluidic devices for fabricating multi‐structural hydrogel microsphereZehao Chen0Zhendong Lv1Zhen Zhang2David A. Weitz3Hongbo Zhang4Yuhui Zhang5Wenguo Cui6School of Mechatronic Engineering and Automation Shanghai University Shanghai P. R. ChinaDepartment of Spine Surgery Renji Hospital Shanghai Jiao Tong University School of Medicine Shanghai P. R. ChinaSchool of Mechatronic Engineering and Automation Shanghai University Shanghai P. R. ChinaDepartment of Physics and Harvard John A. Paulson School of Engineering and Applied Sciences Harvard University Cambridge Massachusetts USAPharmaceutical Sciences Laboratory Åbo Akademi University and Turku Bioscience Centre University of Turku and Åbo Akademi University Turku FinlandSchool of Mechatronic Engineering and Automation Shanghai University Shanghai P. R. ChinaDepartment of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai P. R. ChinaAbstract Hydrogel microspheres are a novel functional material, arousing much attention in various fields. Microfluidics, a technology that controls and manipulates fluids at the micron scale, has emerged as a promising method for fabricating hydrogel microspheres due to its ability to generate uniform microspheres with controlled geometry. With the development of microfluidic devices, more complicated hydrogel microspheres with multiple structures can be constructed. This review presents an overview of advances in microfluidics for designing and engineering hydrogel microspheres. It starts with an introduction to the features of hydrogel microspheres and microfluidic techniques, followed by a discussion of material selection for fabricating microfluidic devices. Then the progress of microfluidic devices for single‐component and composite hydrogel microspheres is described, and the method for optimizing microfluidic devices is also given. Finally, this review discusses the key research directions and applications of microfluidics for hydrogel microsphere in the future.https://doi.org/10.1002/EXP.20210036biomaterialshydrogel microspheresmicrofluidic devicesmicrofluidics |
| spellingShingle | Zehao Chen Zhendong Lv Zhen Zhang David A. Weitz Hongbo Zhang Yuhui Zhang Wenguo Cui Advanced microfluidic devices for fabricating multi‐structural hydrogel microsphere Exploration biomaterials hydrogel microspheres microfluidic devices microfluidics |
| title | Advanced microfluidic devices for fabricating multi‐structural hydrogel microsphere |
| title_full | Advanced microfluidic devices for fabricating multi‐structural hydrogel microsphere |
| title_fullStr | Advanced microfluidic devices for fabricating multi‐structural hydrogel microsphere |
| title_full_unstemmed | Advanced microfluidic devices for fabricating multi‐structural hydrogel microsphere |
| title_short | Advanced microfluidic devices for fabricating multi‐structural hydrogel microsphere |
| title_sort | advanced microfluidic devices for fabricating multi structural hydrogel microsphere |
| topic | biomaterials hydrogel microspheres microfluidic devices microfluidics |
| url | https://doi.org/10.1002/EXP.20210036 |
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