Empagliflozin Attenuates Neointima Formation After Arterial Injury and Inhibits Smooth Muscle Cell Proliferation and Migration by Suppressing Platelet‐Derived Growth Factor–Related Signaling

Empagliflozin Attenuates Neointima Formation After Arterial Injury and Inhibits Smooth Muscle Cell Proliferation and Migration by Suppressing Platelet‐Derived Growth Factor–Related Signaling

Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce cardiovascular events. However, the precise mechanisms beyond glycemic control are not fully understood. The objective of this study was to determine the role of PDGF (platelet‐derived growth factor)–related signaling in empaglifloz...

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Bibliographic Details
Main Authors: Gwo‐Jyh Chang, Wei‐Jan Chen, Yu‐Juei Hsu, Ying‐Hwa Chen
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
empagliflozin
neointima formation
platelet‐derived growth factor
sodium–glucose cotransporter 2
vascular smooth muscle cells
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.035044

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.124.035044

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