Gi-protein-coupled β<sub>1</sub>-adrenergic receptor: re-understanding the selectivity of β<sub>1</sub>-adrenergic receptor to G protein

Gi-protein-coupled β<sub>1</sub>-adrenergic receptor: re-understanding the selectivity of β<sub>1</sub>-adrenergic receptor to G protein

β<sub>1</sub>-adrenergic receptor (β<sub>1</sub>-AR), a member in the family of G-protein-coupled receptors, is a transmembrane receptor of great significance in the heart. Physiologically, catecholamines activate β<sub>1</sub>-AR to initiate a positive chronotrop...

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Bibliographic Details
Main Authors: Chen Hao, Zhang Suli, Hou Ruiqi, Liu Huirong
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-08-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
β<sub>1</sub>-adrenergic receptor
Gi protein
G protein switch
signal transduction
cardioprotective effect
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022096

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