Dosage consideration for transcranial direct current stimulation in post-stroke dysphagia: A systematic review and network meta-analysis
ObjectiveThis systematic review and network meta-analysis sought to determine the efficacy of different intensities of transcranial direct current stimulation (tDCS) in patients with dysphagia after stroke to improve swallowing function.MethodsRandomized-controlled trials (RCTs) of tDCS in post-stro...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2023.1098831/full |
| _version_ | 1797944942915485696 |
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| author | Jianwei Xie Chiteng Zhou Gilbert Ngaruwenayo Minghui Wu Xiaoyu Jiang Xiaohan Li |
| author_facet | Jianwei Xie Chiteng Zhou Gilbert Ngaruwenayo Minghui Wu Xiaoyu Jiang Xiaohan Li |
| author_sort | Jianwei Xie |
| collection | DOAJ |
| description | ObjectiveThis systematic review and network meta-analysis sought to determine the efficacy of different intensities of transcranial direct current stimulation (tDCS) in patients with dysphagia after stroke to improve swallowing function.MethodsRandomized-controlled trials (RCTs) of tDCS in post-stroke dysphagia were searched from Pubmed, EMBASE, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature Service System (SinoMed), Wanfang database, and Chinese Scientific Journals Database (VIP) from databases' inception to June 22, 2022. Article screening, data extraction, and article quality evaluation were completed by 2 independent researchers. Network meta-analysis was performed using Stata.ResultsA final total of 20 studies involving 838 stroke patients were included. The included control interventions were sham tDCS and conventional therapy (CT). Network meta-analysis showed that 20 min of 1.2, 1.4, 1.5, 1.6, and 2 mA anodal tDCS and 30 min of 2 mA anodal tDCS significantly improved post-stroke dysphagia compared with CT (all P < 0.05). In addition, 20 min of 1, 1.4, 1.6, and 2 mA anodal tDCS also significantly improved post-stroke dysphagia compared with sham tDCS (all P < 0.05). Our results demonstrated that 20 min of stimulation at 1.4 mA was the optimal parameters for anodal tDCS and exhibited superior efficacy to CT [SMD = 1.08, 95% CI (0.46, 1.69)] and sham tDCS [SMD = 1.45, 95% CI (0.54, 2.36)].ConclusionDifferent durations and intensities of anodal tDCS are effective in improving post-stroke dysphagia. However, 20 min of tDCS at 1.4 mA may be the optimal regimen.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/#recordDetails, identifier CRD42022342506. |
| first_indexed | 2024-04-10T20:47:34Z |
| format | Article |
| id | doaj.art-fc8b7ba788c14b7aa668fdfc532e9a3a |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-10T20:47:34Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-fc8b7ba788c14b7aa668fdfc532e9a3a2023-01-24T07:31:36ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-01-011410.3389/fneur.2023.10988311098831Dosage consideration for transcranial direct current stimulation in post-stroke dysphagia: A systematic review and network meta-analysisJianwei Xie0Chiteng Zhou1Gilbert Ngaruwenayo2Minghui Wu3Xiaoyu Jiang4Xiaohan Li5School of Nursing, China Medical University, Shenyang, ChinaSchool of Nursing, China Medical University, Shenyang, ChinaThe First Clinical College, China Medical University, Shenyang, ChinaGeneral Hospital of Pingmei Shenma Group, Pingdingshan, ChinaSchool of Nursing, China Medical University, Shenyang, ChinaSchool of Nursing, China Medical University, Shenyang, ChinaObjectiveThis systematic review and network meta-analysis sought to determine the efficacy of different intensities of transcranial direct current stimulation (tDCS) in patients with dysphagia after stroke to improve swallowing function.MethodsRandomized-controlled trials (RCTs) of tDCS in post-stroke dysphagia were searched from Pubmed, EMBASE, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature Service System (SinoMed), Wanfang database, and Chinese Scientific Journals Database (VIP) from databases' inception to June 22, 2022. Article screening, data extraction, and article quality evaluation were completed by 2 independent researchers. Network meta-analysis was performed using Stata.ResultsA final total of 20 studies involving 838 stroke patients were included. The included control interventions were sham tDCS and conventional therapy (CT). Network meta-analysis showed that 20 min of 1.2, 1.4, 1.5, 1.6, and 2 mA anodal tDCS and 30 min of 2 mA anodal tDCS significantly improved post-stroke dysphagia compared with CT (all P < 0.05). In addition, 20 min of 1, 1.4, 1.6, and 2 mA anodal tDCS also significantly improved post-stroke dysphagia compared with sham tDCS (all P < 0.05). Our results demonstrated that 20 min of stimulation at 1.4 mA was the optimal parameters for anodal tDCS and exhibited superior efficacy to CT [SMD = 1.08, 95% CI (0.46, 1.69)] and sham tDCS [SMD = 1.45, 95% CI (0.54, 2.36)].ConclusionDifferent durations and intensities of anodal tDCS are effective in improving post-stroke dysphagia. However, 20 min of tDCS at 1.4 mA may be the optimal regimen.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/#recordDetails, identifier CRD42022342506.https://www.frontiersin.org/articles/10.3389/fneur.2023.1098831/fulldosage considerationtranscranial direct current stimulationpost-stroke dysphagiasystematic reviewnetwork meta-analysis |
| spellingShingle | Jianwei Xie Chiteng Zhou Gilbert Ngaruwenayo Minghui Wu Xiaoyu Jiang Xiaohan Li Dosage consideration for transcranial direct current stimulation in post-stroke dysphagia: A systematic review and network meta-analysis Frontiers in Neurology dosage consideration transcranial direct current stimulation post-stroke dysphagia systematic review network meta-analysis |
| title | Dosage consideration for transcranial direct current stimulation in post-stroke dysphagia: A systematic review and network meta-analysis |
| title_full | Dosage consideration for transcranial direct current stimulation in post-stroke dysphagia: A systematic review and network meta-analysis |
| title_fullStr | Dosage consideration for transcranial direct current stimulation in post-stroke dysphagia: A systematic review and network meta-analysis |
| title_full_unstemmed | Dosage consideration for transcranial direct current stimulation in post-stroke dysphagia: A systematic review and network meta-analysis |
| title_short | Dosage consideration for transcranial direct current stimulation in post-stroke dysphagia: A systematic review and network meta-analysis |
| title_sort | dosage consideration for transcranial direct current stimulation in post stroke dysphagia a systematic review and network meta analysis |
| topic | dosage consideration transcranial direct current stimulation post-stroke dysphagia systematic review network meta-analysis |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2023.1098831/full |
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