An alternative method for assessing the equivalence among treatments in survival analysis
This work aims to evaluate the use of parametric models instead of a nonparametric procedure to adjust survival curves related to different treatments, and to verify the equivalence among treatments by the multivariate method of cluster analysis. The dataset used to validate the method was obtained...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Universidade Federal de Santa Maria
2013-09-01
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| Series: | Ciência Rural |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013000900004&lng=en&tlng=en |
| _version_ | 1819089216762544128 |
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| author | Luiz Alexandre Peternelli Flávia Sílvia Corrêa Tomaz Diego Paiva Bernardes Gilson Fernandes da Silva Fabricia Gonçalves Lacerda |
| author_facet | Luiz Alexandre Peternelli Flávia Sílvia Corrêa Tomaz Diego Paiva Bernardes Gilson Fernandes da Silva Fabricia Gonçalves Lacerda |
| author_sort | Luiz Alexandre Peternelli |
| collection | DOAJ |
| description | This work aims to evaluate the use of parametric models instead of a nonparametric procedure to adjust survival curves related to different treatments, and to verify the equivalence among treatments by the multivariate method of cluster analysis. The dataset used to validate the method was obtained from a laboratory experiment with cutting ants. Eight colonies of cutting ants were used, each one receiving different treatments. The exponential, Weibull, log-normal, and logistic models were adjusted for each treatment, along with the usual Kaplan-Meier adjustment. The logistic model used was the best option for evaluating the survival of the ants. Therefore, this model was adjusted for each treatment. The estimates of the parameters of each adjusted model were clustered using Ward's method of multivariate technique of cluster analysis. Finally, heuristic techniques for choosing the number of clusters were applied in order to define the sets of equivalent treatments. For the dataset used, the proposed method was less laborious and as efficient as the logrank for the comparison of many survival curves. |
| first_indexed | 2024-12-21T22:04:25Z |
| format | Article |
| id | doaj.art-fc8eab6a9fb64f29bfa5929234e5a858 |
| institution | Directory Open Access Journal |
| issn | 1678-4596 |
| language | English |
| last_indexed | 2024-12-21T22:04:25Z |
| publishDate | 2013-09-01 |
| publisher | Universidade Federal de Santa Maria |
| record_format | Article |
| series | Ciência Rural |
| spelling | doaj.art-fc8eab6a9fb64f29bfa5929234e5a8582022-12-21T18:48:45ZengUniversidade Federal de Santa MariaCiência Rural1678-45962013-09-014391553156010.1590/S0103-84782013000900004S0103-84782013000900004An alternative method for assessing the equivalence among treatments in survival analysisLuiz Alexandre Peternelli0Flávia Sílvia Corrêa Tomaz1Diego Paiva Bernardes2Gilson Fernandes da Silva3Fabricia Gonçalves Lacerda4Universidade Federal de ViçosaUniversidade Federal de Ouro PretoUniversidade Federal de ViçosaUniversidade Federal do Espírito SantoUniversidade Federal do Espírito SantoThis work aims to evaluate the use of parametric models instead of a nonparametric procedure to adjust survival curves related to different treatments, and to verify the equivalence among treatments by the multivariate method of cluster analysis. The dataset used to validate the method was obtained from a laboratory experiment with cutting ants. Eight colonies of cutting ants were used, each one receiving different treatments. The exponential, Weibull, log-normal, and logistic models were adjusted for each treatment, along with the usual Kaplan-Meier adjustment. The logistic model used was the best option for evaluating the survival of the ants. Therefore, this model was adjusted for each treatment. The estimates of the parameters of each adjusted model were clustered using Ward's method of multivariate technique of cluster analysis. Finally, heuristic techniques for choosing the number of clusters were applied in order to define the sets of equivalent treatments. For the dataset used, the proposed method was less laborious and as efficient as the logrank for the comparison of many survival curves.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013000900004&lng=en&tlng=enteste logrankanálise de agrupamentocomparação de curvas |
| spellingShingle | Luiz Alexandre Peternelli Flávia Sílvia Corrêa Tomaz Diego Paiva Bernardes Gilson Fernandes da Silva Fabricia Gonçalves Lacerda An alternative method for assessing the equivalence among treatments in survival analysis Ciência Rural teste logrank análise de agrupamento comparação de curvas |
| title | An alternative method for assessing the equivalence among treatments in survival analysis |
| title_full | An alternative method for assessing the equivalence among treatments in survival analysis |
| title_fullStr | An alternative method for assessing the equivalence among treatments in survival analysis |
| title_full_unstemmed | An alternative method for assessing the equivalence among treatments in survival analysis |
| title_short | An alternative method for assessing the equivalence among treatments in survival analysis |
| title_sort | alternative method for assessing the equivalence among treatments in survival analysis |
| topic | teste logrank análise de agrupamento comparação de curvas |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013000900004&lng=en&tlng=en |
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