Results of the ADVANCE trial and interventional observational program ADVANCE-ON: whether our understanding of the relationship of glycemic factors and the risk of vascular complications in patients with type 2 diabetes has changed?
The results from the analysis of the ADVANCE trial and post-intervention program ADVANCE-ON are presented in this article. These studies are dedicated to study the effect of intensive glycemic control on the incidence of micro- and macrovascular events in patients with type 2 diabetes mellitus and e...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Endocrinology Research Centre
2015-12-01
|
| Series: | Сахарный диабет |
| Subjects: | |
| Online Access: | https://www.dia-endojournals.ru/jour/article/view/7696 |
| _version_ | 1797255251893420032 |
|---|---|
| author | Marina Vladimirovna Shestakova Yuriy Shavkatovich Khalimov |
| author_facet | Marina Vladimirovna Shestakova Yuriy Shavkatovich Khalimov |
| author_sort | Marina Vladimirovna Shestakova |
| collection | DOAJ |
| description | The results from the analysis of the ADVANCE trial and post-intervention program ADVANCE-ON are presented in this article. These studies are dedicated to study the effect of intensive glycemic control on the incidence of micro- and macrovascular events in patients with type 2 diabetes mellitus and evaluation of long-term results of intensive glycemic control. We discuss the progress of views on the impact of glycemic control on the development of cardiovascular complications. According to the analysis of the research results, gliclazide MR is safe in patients with type 2 diabetes at high risk for cardiovascular complications. |
| first_indexed | 2024-03-08T15:20:52Z |
| format | Article |
| id | doaj.art-fc8ec502d4c34c8ba368918a15a2a12e |
| institution | Directory Open Access Journal |
| issn | 2072-0351 2072-0378 |
| language | English |
| last_indexed | 2024-04-24T22:02:53Z |
| publishDate | 2015-12-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj.art-fc8ec502d4c34c8ba368918a15a2a12e2024-03-20T11:48:00ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782015-12-0118411912410.14341/DM76967278Results of the ADVANCE trial and interventional observational program ADVANCE-ON: whether our understanding of the relationship of glycemic factors and the risk of vascular complications in patients with type 2 diabetes has changed?Marina Vladimirovna Shestakova0Yuriy Shavkatovich Khalimov1Endocrinology Research Centre; Sechenov First Moscow State Medical UniversityMilitary medical academy of S.M. KirovThe results from the analysis of the ADVANCE trial and post-intervention program ADVANCE-ON are presented in this article. These studies are dedicated to study the effect of intensive glycemic control on the incidence of micro- and macrovascular events in patients with type 2 diabetes mellitus and evaluation of long-term results of intensive glycemic control. We discuss the progress of views on the impact of glycemic control on the development of cardiovascular complications. According to the analysis of the research results, gliclazide MR is safe in patients with type 2 diabetes at high risk for cardiovascular complications.https://www.dia-endojournals.ru/jour/article/view/7696type 2 diabetesadvanceadvance-ondrugs sulfonylureasgliclazide |
| spellingShingle | Marina Vladimirovna Shestakova Yuriy Shavkatovich Khalimov Results of the ADVANCE trial and interventional observational program ADVANCE-ON: whether our understanding of the relationship of glycemic factors and the risk of vascular complications in patients with type 2 diabetes has changed? Сахарный диабет type 2 diabetes advance advance-on drugs sulfonylureas gliclazide |
| title | Results of the ADVANCE trial and interventional observational program ADVANCE-ON: whether our understanding of the relationship of glycemic factors and the risk of vascular complications in patients with type 2 diabetes has changed? |
| title_full | Results of the ADVANCE trial and interventional observational program ADVANCE-ON: whether our understanding of the relationship of glycemic factors and the risk of vascular complications in patients with type 2 diabetes has changed? |
| title_fullStr | Results of the ADVANCE trial and interventional observational program ADVANCE-ON: whether our understanding of the relationship of glycemic factors and the risk of vascular complications in patients with type 2 diabetes has changed? |
| title_full_unstemmed | Results of the ADVANCE trial and interventional observational program ADVANCE-ON: whether our understanding of the relationship of glycemic factors and the risk of vascular complications in patients with type 2 diabetes has changed? |
| title_short | Results of the ADVANCE trial and interventional observational program ADVANCE-ON: whether our understanding of the relationship of glycemic factors and the risk of vascular complications in patients with type 2 diabetes has changed? |
| title_sort | results of the advance trial and interventional observational program advance on whether our understanding of the relationship of glycemic factors and the risk of vascular complications in patients with type 2 diabetes has changed |
| topic | type 2 diabetes advance advance-on drugs sulfonylureas gliclazide |
| url | https://www.dia-endojournals.ru/jour/article/view/7696 |
| work_keys_str_mv | AT marinavladimirovnashestakova resultsoftheadvancetrialandinterventionalobservationalprogramadvanceonwhetherourunderstandingoftherelationshipofglycemicfactorsandtheriskofvascularcomplicationsinpatientswithtype2diabeteshaschanged AT yuriyshavkatovichkhalimov resultsoftheadvancetrialandinterventionalobservationalprogramadvanceonwhetherourunderstandingoftherelationshipofglycemicfactorsandtheriskofvascularcomplicationsinpatientswithtype2diabeteshaschanged |