Development and Validation of Two Optimized Multiplexed Serologic Assays for the 9-Valent Human Papillomavirus Vaccine Types

Development and Validation of Two Optimized Multiplexed Serologic Assays for the 9-Valent Human Papillomavirus Vaccine Types

ABSTRACT Two multiplex immunoassays are routinely used to assess antibody responses in clinical trials of the 9-valent human papillomavirus (9vHPV) vaccine. The HPV6/11/16/18/31/33/45/52/58 competitive Luminex immunoassay (HPV-9 cLIA) and HPV6/11/16/18/31/33/45/52/58 total immunoglobulin G Luminex i...

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Bibliographic Details
Main Authors: Katrina M. Nolan, Brent Seaton, Joseph Antonello, Yuhua Zhang, Lauren Cook, Krystyn Delfino, Leonard J. Rubinstein, Kyeongmi Cheon, Thomas Group, Alain Luxembourg, Sheri Dubey
Format: Article
Language:English
Published: American Society for Microbiology 2023-04-01
Series:mSphere
Subjects:
9-valent human papillomavirus vaccine
competitive Luminex immunoassay
human papillomavirus
immunogenicity
total immunoglobulin G immunoassay
Online Access:https://journals.asm.org/doi/10.1128/msphere.00962-21

Internet

https://journals.asm.org/doi/10.1128/msphere.00962-21

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