Imiglucerase in the treatment of Gaucher disease: a history and perspective

Imiglucerase in the treatment of Gaucher disease: a history and perspective

Patrick B Deegan, Timothy M CoxDepartment of Medicine, University of Cambridge, Lysosomal Disorders Unit, Addenbrooke&#39;s NHS Foundation Hospitals Trust, Cambridge, UKAbstract: The scientific and therapeutic development of imiglucerase (Cerezyme&reg;) by the Genzyme Corporation is...

Full description

Bibliographic Details
Main Authors:	Deegan PB, Cox TM
Format:	Article
Language:	English
Published:	Dove Medical Press 2012-04-01
Series:	Drug Design, Development and Therapy
Online Access:	http://www.dovepress.com/imiglucerase-in-the-treatment-of-gaucher-disease-a-history-and-perspec-a9729

Similar Items

Review of the safety and efficacy of imiglucerase treatment of Gaucher disease
by: Deborah Elstein, et al.
Published: (2009-08-01)

The International Collaborative Gaucher Group GRAF (Gaucher Risk Assessment for Fracture) score: a composite risk score for assessing adult fracture risk in imiglucerase-treated Gaucher disease type 1 patients
by: Patrick Deegan, et al.
Published: (2021-02-01)

Comparative therapeutic effects of velaglucerase alfa and imiglucerase in a Gaucher disease mouse model.
by: You-Hai Xu, et al.
Published: (2010-05-01)

Reversal of life-threatening hepatopulmonary syndrome in Gaucher disease by imiglucerase enzyme replacement therapy
by: Amal El Beshlawy, et al.
Published: (2019-09-01)

Impact on bone microarchitecture and failure load in a patient with type I Gaucher disease who switched from Imiglucerase to Eliglustat
by: Karamjot Sidhu, et al.
Published: (2020-09-01)

Gaucher disease: transcriptome analyses using microarray or mRNA sequencing in a Gba1 mutant mouse model treated with velaglucerase alfa or imiglucerase.
by: Nupur Dasgupta, et al.
Published: (2013-01-01)

Internalization of Recombinant Imiglucerase into Mouse Peritoneal Macrophages and L929 Mouse Fibroblasts
by: I. V. Lyagoskin, et al.
Published: (2020-03-01)

Characteristics of 26 patients with type 3 Gaucher disease: A descriptive analysis from the Gaucher Outcome Survey
by: Ida Vanessa D. Schwartz, et al.
Published: (2018-03-01)

Gaucher Disease and Gaucher Cells
by: Sevgi Gözdaşoğlu
Published: (2015-05-01)

In-depth phenotyping for clinical stratification of Gaucher disease
by: Simona D’Amore, et al.
Published: (2021-10-01)

Neuropathological Features of Gaucher Disease and Gaucher Disease with Parkinsonism
by: Makaila L. Furderer, et al.
Published: (2022-05-01)

Gaucher disease.
by: Butters, T
Published: (2007)

Gaucher Disease
by: Guilherme Henrique Hencklain Fonseca, et al.
Published: (2007-03-01)

Gaucher′s disease
by: Vijay Bohra, et al.
Published: (2011-01-01)

Treatment options for patients with Gaucher disease
by: Rabah M. Shawky, et al.
Published: (2016-07-01)

Switching between Enzyme Replacement Therapies and Substrate Reduction Therapies in Patients with Gaucher Disease: Data from the Gaucher Outcome Survey (GOS)
by: Derralynn A. Hughes, et al.
Published: (2022-08-01)

Gaucher’s Disease – current state of knowledge and future perspectives?
by: Katarzyna Szymańska, et al.
Published: (2024-03-01)

Macitentan in the treatment of pulmonary hypertension in Gaucher's disease
by: Gokay Taylan, et al.
Published: (2020-01-01)

Women with Gaucher Disease
by: Maria del Mar Meijon-Ortigueira, et al.
Published: (2024-03-01)

Gaucher Disease for Hematologists
by: Gül Nihal Özdemir, et al.
Published: (2022-05-01)

PB2551: GAUCHER DISEASE CURRICULUM: INCORPORATING GAUCHER DISEASE IN THE FIELD OF HEMATOLOGY
by: Argiris Symeonidis, et al.
Published: (2023-08-01)

Lung Involvement in Gaucher Disease
by: Mahnaz Pejman Sani, et al.
Published: (2020-04-01)

Enzyme replacement in Gaucher disease.
by: Ernest Beutler
Published: (2004-11-01)

Prevalence and management of Gaucher disease
by: Burrow TA, et al.
Published: (2011-06-01)

Management algorithms for gaucher disease
by: Ayman Alhejazi, et al.
Published: (2020-01-01)

Hemorrhagic Aspects of Gaucher Disease
by: Hanna Rsenbaum
Published: (2014-10-01)

Splenic lipids in Gaucher's disease
by: N.G. Kennaway, et al.
Published: (1968-11-01)

Exodontia in patient with Gaucher's disease
by: Guacyra Machado Lisboa, et al.
Published: (2011-12-01)

The structure of cerebrosides in Gaucher's disease*
by: G.V. Marinetti, et al.
Published: (1960-04-01)

Gaucher's disease management protocol
by: E. A. Lukina, et al.
Published: (2022-11-01)

The use of Ambroxol for the treatment of Gaucher disease: A systematic review
by: Diego Agustín Abelleyra Lastoria, et al.
Published: (2024-02-01)

Gaucher Cells or Pseudo-Gaucher Cells: That's the Question
by: Deniz Gören Şahin, et al.
Published: (2014-12-01)

Cirurgias conservadoras do baço para tratamento da doença de Gaucher Partial splenectomy in the treatment of Gaucher's disease
by: Andy Petroianu
Published: (2004-03-01)

DOCTOR’S AUTOMATIZED WORK PLACE FOR THE TREATMENT OF PATIENTS WITH GAUCHER DISEASE
by: N. H. Horovenko, et al.
Published: (2015-05-01)

Eliglustat tartrate for the treatment of adults with type 1 Gaucher disease
by: Bennett LL, et al.
Published: (2015-08-01)

Identification of Modifier Genes in a Mouse Model of Gaucher Disease
by: Andrés D. Klein, et al.
Published: (2016-09-01)

Failure of treatment of Coxa Vara in Gauchers Disease: A Case Report
by: Sachin Khullar, et al.
Published: (2012-02-01)

Corrective surgery for kyphosis in a case of Gaucher's disease without history of vertebral compression fractures
by: Kenyu Ito, et al.
Published: (2017-10-01)

Animal Models for the Study of Gaucher Disease
by: Or Cabasso, et al.
Published: (2023-11-01)

Gaucher Disease in Internal Medicine and Dentistry
by: Michele Basilicata, et al.
Published: (2023-03-01)