The utility of diffusion weighted MRI and apparent diffusion coefficient in characterization of breast masses
Purpose: This study aimed to emphasize the value of DW-MRI, ADC values in differentiation of various breast masses. Patients and methods: Between “June 2013 to January 2015”, 50 consecutive patients with suspicious breast lesions underwent DW-MRI and ADC with the measurement of ADC values. All patie...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2015-12-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0378603X15001369 |
| _version_ | 1818293475514253312 |
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| author | Moustafa A. Kader A. Wahab Hoda Abdel Kareem Ebtesam Esmail Hassan |
| author_facet | Moustafa A. Kader A. Wahab Hoda Abdel Kareem Ebtesam Esmail Hassan |
| author_sort | Moustafa A. Kader A. Wahab |
| collection | DOAJ |
| description | Purpose: This study aimed to emphasize the value of DW-MRI, ADC values in differentiation of various breast masses.
Patients and methods: Between “June 2013 to January 2015”, 50 consecutive patients with suspicious breast lesions underwent DW-MRI and ADC with the measurement of ADC values. All patients were examined with 1.5 Tesla MRI machine using breast coil. The images were obtained with b-values 0 and 750 s/mm2. The ADC values were calculated for breast lesions and axillary LNs. The results were correlated with the histopathology results which were taken as gold standard.
Results: In the studied 50 lesions, 20 were benign and 30 were malignant. The most frequent benign lesion was fibroadenoma (16%) and the most frequent malignant lesion was invasive duct carcinoma (36%). The mean ADC value for benign lesions was 1.6 ± 0.33 × 10−3 mm2/s while the mean ADC value for malignant lesions was 0.84 ± 0.25 × 10−3 mm2/s. The ROC curve showed that the best ADC cut-off value between benign and malignant lesions was 1.02 × 10−3 mm2/s with sensitivity, specificity, PPV, NPV and accuracy of 90%, 95%, 100%, 90.4% and 92% respectively.
Conclusion: DW-MRI with ADC values measurement was considered a useful tool for accurate differentiation of various breast masses. |
| first_indexed | 2024-12-13T03:16:27Z |
| format | Article |
| id | doaj.art-fc94579333894da092dc8d23fe133153 |
| institution | Directory Open Access Journal |
| issn | 0378-603X |
| language | English |
| last_indexed | 2024-12-13T03:16:27Z |
| publishDate | 2015-12-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-fc94579333894da092dc8d23fe1331532022-12-22T00:01:27ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2015-12-014641257126510.1016/j.ejrnm.2015.06.016The utility of diffusion weighted MRI and apparent diffusion coefficient in characterization of breast massesMoustafa A. Kader A. Wahab0Hoda Abdel Kareem1Ebtesam Esmail Hassan2Department of Radiology, El Minia University, EgyptDepartment of Radiology, South Vally University, EgyptPublic Health and Preventive Medicine, El Minia University, EgyptPurpose: This study aimed to emphasize the value of DW-MRI, ADC values in differentiation of various breast masses. Patients and methods: Between “June 2013 to January 2015”, 50 consecutive patients with suspicious breast lesions underwent DW-MRI and ADC with the measurement of ADC values. All patients were examined with 1.5 Tesla MRI machine using breast coil. The images were obtained with b-values 0 and 750 s/mm2. The ADC values were calculated for breast lesions and axillary LNs. The results were correlated with the histopathology results which were taken as gold standard. Results: In the studied 50 lesions, 20 were benign and 30 were malignant. The most frequent benign lesion was fibroadenoma (16%) and the most frequent malignant lesion was invasive duct carcinoma (36%). The mean ADC value for benign lesions was 1.6 ± 0.33 × 10−3 mm2/s while the mean ADC value for malignant lesions was 0.84 ± 0.25 × 10−3 mm2/s. The ROC curve showed that the best ADC cut-off value between benign and malignant lesions was 1.02 × 10−3 mm2/s with sensitivity, specificity, PPV, NPV and accuracy of 90%, 95%, 100%, 90.4% and 92% respectively. Conclusion: DW-MRI with ADC values measurement was considered a useful tool for accurate differentiation of various breast masses.http://www.sciencedirect.com/science/article/pii/S0378603X15001369DW-MRIADC map and valueBreast masses |
| spellingShingle | Moustafa A. Kader A. Wahab Hoda Abdel Kareem Ebtesam Esmail Hassan The utility of diffusion weighted MRI and apparent diffusion coefficient in characterization of breast masses The Egyptian Journal of Radiology and Nuclear Medicine DW-MRI ADC map and value Breast masses |
| title | The utility of diffusion weighted MRI and apparent diffusion coefficient in characterization of breast masses |
| title_full | The utility of diffusion weighted MRI and apparent diffusion coefficient in characterization of breast masses |
| title_fullStr | The utility of diffusion weighted MRI and apparent diffusion coefficient in characterization of breast masses |
| title_full_unstemmed | The utility of diffusion weighted MRI and apparent diffusion coefficient in characterization of breast masses |
| title_short | The utility of diffusion weighted MRI and apparent diffusion coefficient in characterization of breast masses |
| title_sort | utility of diffusion weighted mri and apparent diffusion coefficient in characterization of breast masses |
| topic | DW-MRI ADC map and value Breast masses |
| url | http://www.sciencedirect.com/science/article/pii/S0378603X15001369 |
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