Case Reports on Black Fungus of the Gastrointestinal Tract: A New Complication in COVID-19 Patients
Gastrointestinal mucormycosis is a rare disease with a significant mortality rate, even when promptly diagnosed and treated. An unusual complication was observed in India during the second wave of coronavirus disease 2019 (COVID-19). Two incidences of gastric mucormycosis were found. A 53-year-old m...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Jin Publishing & Printing Co.
2023-05-01
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| Series: | The Korean Journal of Gastroenterology |
| Subjects: | |
| Online Access: | https://www.kjg.or.kr/journal/view.html?uid=5919&vmd=Full |
| _version_ | 1797263571625705472 |
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| author | Sachin Arora Ashish Singh Pallavi Prasad Rahul Rajneesh Singh |
| author_facet | Sachin Arora Ashish Singh Pallavi Prasad Rahul Rajneesh Singh |
| author_sort | Sachin Arora |
| collection | DOAJ |
| description | Gastrointestinal mucormycosis is a rare disease with a significant mortality rate, even when promptly diagnosed and treated. An unusual complication was observed in India during the second wave of coronavirus disease 2019 (COVID-19). Two incidences of gastric mucormycosis were found. A 53-year-old male patient with a history of COVID-19 one month earlier came into the intensive care unit. After admission, the patient developed hematemesis, which was initially treated with blood transfusions and digital subtraction angiography embolization. Esophagogastroduodenoscopy (EGD) revealed a large ulcer with a clot in the stomach. During an exploratory laparotomy, the proximal stomach was necrotic. Histopathological examination confirmed mucormycosis. The patient was started on antifungals, but despite rigorous therapy, the patient died on the tenth postoperative day. Another patient, an 82-year-old male with a history of COVID-19, arrived with hematemesis two weeks earlier and was treated conservatively. EGD revealed a large white-based ulcer with abundant slough along the larger curvature of the body. Mucormycosis was verified by biopsy. He was treated with amphotericin B and isavuconazole. He was discharged after two weeks in a stable condition. Despite quick detection and aggressive treatment, the prognosis is poor. In the second case, prompt diagnosis and treatment saved the patient’s life. |
| first_indexed | 2024-04-25T00:15:08Z |
| format | Article |
| id | doaj.art-fc94b4200b7847cf886bf87df41725df |
| institution | Directory Open Access Journal |
| issn | 1598-9992 2233-6869 |
| language | English |
| last_indexed | 2024-04-25T00:15:08Z |
| publishDate | 2023-05-01 |
| publisher | Jin Publishing & Printing Co. |
| record_format | Article |
| series | The Korean Journal of Gastroenterology |
| spelling | doaj.art-fc94b4200b7847cf886bf87df41725df2024-03-13T06:53:57ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692023-05-0181522122510.4166/kjg.2023.015Case Reports on Black Fungus of the Gastrointestinal Tract: A New Complication in COVID-19 PatientsSachin Arora0Ashish Singh1Pallavi Prasad2Rahul3Rajneesh Singh4Departments of Surgical Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, IndiaDepartments of Surgical Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, IndiaDepartments of Pathology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, IndiaDepartments of Surgical Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, IndiaDepartments of Surgical Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, IndiaGastrointestinal mucormycosis is a rare disease with a significant mortality rate, even when promptly diagnosed and treated. An unusual complication was observed in India during the second wave of coronavirus disease 2019 (COVID-19). Two incidences of gastric mucormycosis were found. A 53-year-old male patient with a history of COVID-19 one month earlier came into the intensive care unit. After admission, the patient developed hematemesis, which was initially treated with blood transfusions and digital subtraction angiography embolization. Esophagogastroduodenoscopy (EGD) revealed a large ulcer with a clot in the stomach. During an exploratory laparotomy, the proximal stomach was necrotic. Histopathological examination confirmed mucormycosis. The patient was started on antifungals, but despite rigorous therapy, the patient died on the tenth postoperative day. Another patient, an 82-year-old male with a history of COVID-19, arrived with hematemesis two weeks earlier and was treated conservatively. EGD revealed a large white-based ulcer with abundant slough along the larger curvature of the body. Mucormycosis was verified by biopsy. He was treated with amphotericin B and isavuconazole. He was discharged after two weeks in a stable condition. Despite quick detection and aggressive treatment, the prognosis is poor. In the second case, prompt diagnosis and treatment saved the patient’s life.https://www.kjg.or.kr/journal/view.html?uid=5919&vmd=Fullcovid-19coronavirusmucormycosisfungusamphotericin b |
| spellingShingle | Sachin Arora Ashish Singh Pallavi Prasad Rahul Rajneesh Singh Case Reports on Black Fungus of the Gastrointestinal Tract: A New Complication in COVID-19 Patients The Korean Journal of Gastroenterology covid-19 coronavirus mucormycosis fungus amphotericin b |
| title | Case Reports on Black Fungus of the Gastrointestinal Tract: A New Complication in COVID-19 Patients |
| title_full | Case Reports on Black Fungus of the Gastrointestinal Tract: A New Complication in COVID-19 Patients |
| title_fullStr | Case Reports on Black Fungus of the Gastrointestinal Tract: A New Complication in COVID-19 Patients |
| title_full_unstemmed | Case Reports on Black Fungus of the Gastrointestinal Tract: A New Complication in COVID-19 Patients |
| title_short | Case Reports on Black Fungus of the Gastrointestinal Tract: A New Complication in COVID-19 Patients |
| title_sort | case reports on black fungus of the gastrointestinal tract a new complication in covid 19 patients |
| topic | covid-19 coronavirus mucormycosis fungus amphotericin b |
| url | https://www.kjg.or.kr/journal/view.html?uid=5919&vmd=Full |
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