A new approach to prostate cancer screening
Prostate cancer screening based on prostate-specific antigen (PSA) testing has been a matter of controversy. Although screening for prostate cancer was effective in reducing mortality, it resulted in overdiagnosis, which translated into unnecessary treatments and numerous adverse effects. As a resul...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2023-08-01
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| Series: | Advances in Laboratory Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/almed-2023-0082 |
| _version_ | 1827796694299836416 |
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| author | Filella Xavier González Álvaro Augé Josep Maria Barco Antonio Carbonell Rosa Gaspar María Jesús Martínez-Peinado Antonio Barrios Clara Pérez Sánchez-Carbayo Marta Santotoribio José Diego Trapé Jaume |
| author_facet | Filella Xavier González Álvaro Augé Josep Maria Barco Antonio Carbonell Rosa Gaspar María Jesús Martínez-Peinado Antonio Barrios Clara Pérez Sánchez-Carbayo Marta Santotoribio José Diego Trapé Jaume |
| author_sort | Filella Xavier |
| collection | DOAJ |
| description | Prostate cancer screening based on prostate-specific antigen (PSA) testing has been a matter of controversy. Although screening for prostate cancer was effective in reducing mortality, it resulted in overdiagnosis, which translated into unnecessary treatments and numerous adverse effects. As a result, recommendations from scientific societies became increasingly restrictive. In the recent years, new approaches to prostate cancer screening have been proposed. These new approaches are aimed at solving the controversy between widespread screening vs. no screening, and reconsidering PSA testing as a screening tool with a good benefit/risk balance. In this context, the European Association of Urology submitted a proposal to the European Commission for prostate cancer screening to be performed as a function of baseline PSA concentrations. The European Commission recently recommended the implementation of organized prostate cancer screening programs for men aged ≤70 years based on PSA values in combination with follow-up magnetic resonance imaging. |
| first_indexed | 2024-03-11T19:10:44Z |
| format | Article |
| id | doaj.art-fc99cdf3128b425898b6d480895844f0 |
| institution | Directory Open Access Journal |
| issn | 2628-491X |
| language | English |
| last_indexed | 2024-03-11T19:10:44Z |
| publishDate | 2023-08-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Advances in Laboratory Medicine |
| spelling | doaj.art-fc99cdf3128b425898b6d480895844f02023-10-09T20:08:32ZengDe GruyterAdvances in Laboratory Medicine2628-491X2023-08-014320721110.1515/almed-2023-0082A new approach to prostate cancer screeningFilella Xavier0González Álvaro1Augé Josep Maria2Barco Antonio3Carbonell Rosa4Gaspar María Jesús5Martínez-Peinado Antonio6Barrios Clara Pérez7Sánchez-Carbayo Marta8Santotoribio José Diego9Trapé Jaume10Service of Biochemistry and Molecular Genetics, CDB, Hospital Clínic de Barcelona, IDIBAPS, Barcelona, SpainService of Biochemistry, Clínica Universidad de Navarra, Pamplona, SpainService of Biochemistry and Molecular Genetics, CDB, Hospital Clínic de Barcelona, IDIBAPS, Barcelona, SpainService of Clinical Biochemistry, Miguel Servet University Hospital, Zaragoza, SpainLaboratory of Biochemistry, San Juan University Hospital, San Juan, Alicante, SpainService of Clinical Analysis, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, SpainClinical Analsysis Management Unit, Section of Molecular Genetics, Reina Sofía University Hospital, Córdoba, SpainLaboratory, Puerta de Hierro University Hospital, Majadahonda, Madrid, SpainDepartment of Health Sciences, Universidad Pontificia, Salamanca, SpainLaboratory, Hospital Universitario Virgen del Rocio, Seville, SpainLaboratory, Althaia Xarxa Assitencial Universitària, Manresa, SpainProstate cancer screening based on prostate-specific antigen (PSA) testing has been a matter of controversy. Although screening for prostate cancer was effective in reducing mortality, it resulted in overdiagnosis, which translated into unnecessary treatments and numerous adverse effects. As a result, recommendations from scientific societies became increasingly restrictive. In the recent years, new approaches to prostate cancer screening have been proposed. These new approaches are aimed at solving the controversy between widespread screening vs. no screening, and reconsidering PSA testing as a screening tool with a good benefit/risk balance. In this context, the European Association of Urology submitted a proposal to the European Commission for prostate cancer screening to be performed as a function of baseline PSA concentrations. The European Commission recently recommended the implementation of organized prostate cancer screening programs for men aged ≤70 years based on PSA values in combination with follow-up magnetic resonance imaging.https://doi.org/10.1515/almed-2023-0082prostate cancerpsascreening |
| spellingShingle | Filella Xavier González Álvaro Augé Josep Maria Barco Antonio Carbonell Rosa Gaspar María Jesús Martínez-Peinado Antonio Barrios Clara Pérez Sánchez-Carbayo Marta Santotoribio José Diego Trapé Jaume A new approach to prostate cancer screening Advances in Laboratory Medicine prostate cancer psa screening |
| title | A new approach to prostate cancer screening |
| title_full | A new approach to prostate cancer screening |
| title_fullStr | A new approach to prostate cancer screening |
| title_full_unstemmed | A new approach to prostate cancer screening |
| title_short | A new approach to prostate cancer screening |
| title_sort | new approach to prostate cancer screening |
| topic | prostate cancer psa screening |
| url | https://doi.org/10.1515/almed-2023-0082 |
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