Phosphatidic Acid Stimulates Lung Cancer Cell Migration through Interaction with the LPA1 Receptor and Subsequent Activation of MAP Kinases and STAT3
Phosphatidic acid (PA) is a key bioactive glycerophospholipid that is implicated in the regulation of vital cell functions such as cell growth, differentiation, and migration, and is involved in a variety of pathologic processes. However, the molecular mechanisms by which PA exerts its pathophysiolo...
Main Authors: | Ana Gomez-Larrauri, Patricia Gangoiti, Laura Camacho, Natalia Presa, Cesar Martin, Antonio Gomez-Muñoz |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-06-01
|
Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/11/7/1804 |
Similar Items
-
Phosphatidic acid formation and signaling in plant cells
by: Y. S. Kolesnikov, et al.
Published: (2024-02-01) -
Screening and identification of host signaling pathways for alleviating influenza-induced production of pro-inflammatory cytokines, IP-10, IL-8, and MCP-1, using a U937 cell-based influenza model
by: Si Chen, et al.
Published: (2025-01-01) -
Anti-Inflammatory Effects of Cannabigerol In Vitro and In Vivo Are Mediated Through the JAK/STAT/NFκB Signaling Pathway
by: Ga Hee Jeong, et al.
Published: (2025-01-01) -
STAT1/STAT3 Gain of Function and Mechanisms of Immune Dysregulation
by: Ayça Kıykım
Published: (2024-04-01) -
Targeting the JAK/STAT Signaling Pathway Using Phytocompounds for Cancer Prevention and Therapy
by: Sankhadip Bose, et al.
Published: (2020-06-01)