Application of Fluorescence Spectroscopy for Assesment of Myocardial Ischemic Injury
Data of experimental assessment of a possibility to use laser-fluorescent analysis of myocardium for detecting alterations caused by ischemia under the conditions of cardiac surgery are presented. It is confirmed that the method of optical biopsy with Nitrogen laser (337 nm) allows registering metab...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Siberian Federal University
2011-06-01
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| Series: | Журнал Сибирского федерального университета: Серия Биология |
| Subjects: | |
| Online Access: | http://elib.sfu-kras.ru/bitstream/2311/2560/1/Salmin.pdf |
| _version_ | 1818543655718223872 |
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| author | Vladimir V. Salmin Alla B. Salmina Alexander A. Fursov Olga V. Frolova Dmitry I. Laletin Maxim A. Fursov Gennady V. Yudin Nataliya A. Malinovskaya Larissa D. Zykova Alexander S. Provorov |
| author_facet | Vladimir V. Salmin Alla B. Salmina Alexander A. Fursov Olga V. Frolova Dmitry I. Laletin Maxim A. Fursov Gennady V. Yudin Nataliya A. Malinovskaya Larissa D. Zykova Alexander S. Provorov |
| author_sort | Vladimir V. Salmin |
| collection | DOAJ |
| description | Data of experimental assessment of a possibility to use laser-fluorescent analysis of myocardium for detecting alterations caused by ischemia under the conditions of cardiac surgery are presented. It is confirmed that the method of optical biopsy with Nitrogen laser (337 nm) allows registering metabolic changes in myocardium associated with alterations in pyridine nucleotides concentrations, dysfunction of hemoproteids, changes in the activity of NAD(P)H-utilizing enzymes, and development of contraction and death of cardiomyocytes. |
| first_indexed | 2024-12-11T22:38:16Z |
| format | Article |
| id | doaj.art-fc9fc1c757f44b87a6766127b4b86e92 |
| institution | Directory Open Access Journal |
| issn | 1997-1389 2313-5530 |
| language | English |
| last_indexed | 2024-12-11T22:38:16Z |
| publishDate | 2011-06-01 |
| publisher | Siberian Federal University |
| record_format | Article |
| series | Журнал Сибирского федерального университета: Серия Биология |
| spelling | doaj.art-fc9fc1c757f44b87a6766127b4b86e922022-12-22T00:47:54ZengSiberian Federal UniversityЖурнал Сибирского федерального университета: Серия Биология1997-13892313-55302011-06-0142142157http://elib.sfu-kras.ru/handle/2311/2560Application of Fluorescence Spectroscopy for Assesment of Myocardial Ischemic InjuryVladimir V. Salmin0Alla B. Salmina1Alexander A. Fursov2Olga V. Frolova3Dmitry I. Laletin4Maxim A. Fursov5Gennady V. Yudin6Nataliya A. Malinovskaya7Larissa D. Zykova8Alexander S. Provorov9Siberian Federal University , 79 Svobodny, Krasnoyarsk, 660041 RussiaKrasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 RussiaKrasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 RussiaKrasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 RussiaKrasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 RussiaKrasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 RussiaKrasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 RussiaKrasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 RussiaKrasnoyarsk State Medical University named after Prof. V.F.Voino-Yasenetsky , 1 P. Zheleznyaka str., Krasnoyarsk, 660022 RussiaSiberian Federal University , 79 Svobodny, Krasnoyarsk, 660041 RussiaData of experimental assessment of a possibility to use laser-fluorescent analysis of myocardium for detecting alterations caused by ischemia under the conditions of cardiac surgery are presented. It is confirmed that the method of optical biopsy with Nitrogen laser (337 nm) allows registering metabolic changes in myocardium associated with alterations in pyridine nucleotides concentrations, dysfunction of hemoproteids, changes in the activity of NAD(P)H-utilizing enzymes, and development of contraction and death of cardiomyocytes.http://elib.sfu-kras.ru/bitstream/2311/2560/1/Salmin.pdfoptical biopsymyocardiumischemianitrogen laser |
| spellingShingle | Vladimir V. Salmin Alla B. Salmina Alexander A. Fursov Olga V. Frolova Dmitry I. Laletin Maxim A. Fursov Gennady V. Yudin Nataliya A. Malinovskaya Larissa D. Zykova Alexander S. Provorov Application of Fluorescence Spectroscopy for Assesment of Myocardial Ischemic Injury Журнал Сибирского федерального университета: Серия Биология optical biopsy myocardium ischemia nitrogen laser |
| title | Application of Fluorescence Spectroscopy for Assesment of Myocardial Ischemic Injury |
| title_full | Application of Fluorescence Spectroscopy for Assesment of Myocardial Ischemic Injury |
| title_fullStr | Application of Fluorescence Spectroscopy for Assesment of Myocardial Ischemic Injury |
| title_full_unstemmed | Application of Fluorescence Spectroscopy for Assesment of Myocardial Ischemic Injury |
| title_short | Application of Fluorescence Spectroscopy for Assesment of Myocardial Ischemic Injury |
| title_sort | application of fluorescence spectroscopy for assesment of myocardial ischemic injury |
| topic | optical biopsy myocardium ischemia nitrogen laser |
| url | http://elib.sfu-kras.ru/bitstream/2311/2560/1/Salmin.pdf |
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