Glutamine deprivation induces ferroptosis in pancreatic cancer cells

Glutamine deprivation induces ferroptosis in pancreatic cancer cells

Ferroptosis is a type of programmed cell death closely related to amino acid metabolism. Pancreatic cancer cells have a strong dependence on glutamine, which serves as a carbon and nitrogen substrate to sustain rapid growth. Glutamine also aids in self-protection mechanisms. However, the effect of g...

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Bibliographic Details
Main Authors: Xiao Zhiwen, Deng Shengming, Liu He, Wang Ruijie, Liu Yu, Dai Zhengjie, Gu Wenchao, Ni Quanxing, Yu Xianjun, Liu Chen, Luo Guopei
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2023-03-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
ferroptosis
glutamine
glutathione
pancreatic cancer
reactive oxygen species
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2023029

Internet

https://www.sciengine.com/doi/10.3724/abbs.2023029

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