Association of Alcohol Consumption With Fat Deposition in a Community-Based Sample of Japanese Men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA)
Background: Excessive alcohol intake has been shown to be associated with cardiovascular disease via metabolic pathways. However, the relationship between alcohol intake and obesity has not been fully elucidated. We aimed to examine the association of alcohol consumption with fat deposition and anth...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Japan Epidemiological Association
2019-06-01
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| Series: | Journal of Epidemiology |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jea/29/6/29_JE20170191/_pdf |
| _version_ | 1828875350664282112 |
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| author | Masaki Sumi Takashi Hisamatsu Akira Fujiyoshi Aya Kadota Naoko Miyagawa Keiko Kondo Sayaka Kadowaki Sentaro Suzuki Sayuki Torii Maryam Zaid Atsushi Sato Hisatomi Arima Tomohiro Terada Katsuyuki Miura Hirotsugu Ueshima |
| author_facet | Masaki Sumi Takashi Hisamatsu Akira Fujiyoshi Aya Kadota Naoko Miyagawa Keiko Kondo Sayaka Kadowaki Sentaro Suzuki Sayuki Torii Maryam Zaid Atsushi Sato Hisatomi Arima Tomohiro Terada Katsuyuki Miura Hirotsugu Ueshima |
| author_sort | Masaki Sumi |
| collection | DOAJ |
| description | Background: Excessive alcohol intake has been shown to be associated with cardiovascular disease via metabolic pathways. However, the relationship between alcohol intake and obesity has not been fully elucidated. We aimed to examine the association of alcohol consumption with fat deposition and anthropometric measures. Methods: From 2006–2008, we conducted a cross-sectional study in a population-based sample of Japanese men aged 40 through 79 years. Areas of abdominal visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were calculated using computed tomography imaging. Based on a questionnaire, we classified participants into five groups according to weekly alcohol consumption, excluding former drinkers: non-drinkers (0 g/week), 0.1–160.9, 161–321.9, 322–482.9, and ≥483 g/week. Multivariable linear regression was used to estimate adjusted means of obesity indices for each group. Results: We analyzed 998 men (mean age and body mass index [BMI], 63.8 years and 23.6 kg/m2, respectively). Higher weekly alcohol consumption was strongly and significantly associated with higher abdominal VAT area, percentage of VAT, and VAT-to-SAT ratio (all P for trend <0.001), and also with waist circumferences and waist-to-hip ratio (P for trend = 0.042 and 0.007, respectively). These associations remained significant after further adjustment for BMI, whereas alcohol consumption had no significant association with abdominal SAT area. Conclusions: Higher alcohol consumption was associated with higher VAT area, VAT%, and VAT-to-SAT ratio, independent of confounders, including BMI, in general Japanese men. These results suggest that alcohol consumption may have a potential adverse effect on visceral fat deposition. |
| first_indexed | 2024-12-13T07:57:21Z |
| format | Article |
| id | doaj.art-fca124d591a94927a9b6f7aad3eb932d |
| institution | Directory Open Access Journal |
| issn | 0917-5040 1349-9092 |
| language | English |
| last_indexed | 2024-12-13T07:57:21Z |
| publishDate | 2019-06-01 |
| publisher | Japan Epidemiological Association |
| record_format | Article |
| series | Journal of Epidemiology |
| spelling | doaj.art-fca124d591a94927a9b6f7aad3eb932d2022-12-21T23:54:31ZengJapan Epidemiological AssociationJournal of Epidemiology0917-50401349-90922019-06-0129620521210.2188/jea.JE20170191Association of Alcohol Consumption With Fat Deposition in a Community-Based Sample of Japanese Men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA)Masaki Sumi0Takashi Hisamatsu1Akira Fujiyoshi2Aya Kadota3Naoko Miyagawa4Keiko Kondo5Sayaka Kadowaki6Sentaro Suzuki7Sayuki Torii8Maryam Zaid9Atsushi Sato10Hisatomi Arima11Tomohiro Terada12Katsuyuki Miura13Hirotsugu Ueshima14Department of Public Health, Shiga University of Medical Science, Shiga, JapanDepartment of Public Health, Shiga University of Medical Science, Shiga, JapanDepartment of Public Health, Shiga University of Medical Science, Shiga, JapanCenter for Epidemiologic Research in Asia, Shiga University of Medical Science, Shiga, JapanDepartment of Public Health, Shiga University of Medical Science, Shiga, JapanDepartment of Public Health, Shiga University of Medical Science, Shiga, JapanDepartment of Public Health, Shiga University of Medical Science, Shiga, JapanDepartment of Public Health, Shiga University of Medical Science, Shiga, JapanDepartment of Public Health, Shiga University of Medical Science, Shiga, JapanCenter for Epidemiologic Research in Asia, Shiga University of Medical Science, Shiga, JapanDepartment of Public Health, Shiga University of Medical Science, Shiga, JapanDepartment of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University, Fukuoka, JapanDepartment of Pharmacy, Shiga University of Medical Science Hospital, Shiga, JapanDepartment of Public Health, Shiga University of Medical Science, Shiga, JapanDepartment of Public Health, Shiga University of Medical Science, Shiga, JapanBackground: Excessive alcohol intake has been shown to be associated with cardiovascular disease via metabolic pathways. However, the relationship between alcohol intake and obesity has not been fully elucidated. We aimed to examine the association of alcohol consumption with fat deposition and anthropometric measures. Methods: From 2006–2008, we conducted a cross-sectional study in a population-based sample of Japanese men aged 40 through 79 years. Areas of abdominal visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were calculated using computed tomography imaging. Based on a questionnaire, we classified participants into five groups according to weekly alcohol consumption, excluding former drinkers: non-drinkers (0 g/week), 0.1–160.9, 161–321.9, 322–482.9, and ≥483 g/week. Multivariable linear regression was used to estimate adjusted means of obesity indices for each group. Results: We analyzed 998 men (mean age and body mass index [BMI], 63.8 years and 23.6 kg/m2, respectively). Higher weekly alcohol consumption was strongly and significantly associated with higher abdominal VAT area, percentage of VAT, and VAT-to-SAT ratio (all P for trend <0.001), and also with waist circumferences and waist-to-hip ratio (P for trend = 0.042 and 0.007, respectively). These associations remained significant after further adjustment for BMI, whereas alcohol consumption had no significant association with abdominal SAT area. Conclusions: Higher alcohol consumption was associated with higher VAT area, VAT%, and VAT-to-SAT ratio, independent of confounders, including BMI, in general Japanese men. These results suggest that alcohol consumption may have a potential adverse effect on visceral fat deposition.https://www.jstage.jst.go.jp/article/jea/29/6/29_JE20170191/_pdfalcohol consumptionvisceral adipose tissuefat depositionanthropometric obesity indice |
| spellingShingle | Masaki Sumi Takashi Hisamatsu Akira Fujiyoshi Aya Kadota Naoko Miyagawa Keiko Kondo Sayaka Kadowaki Sentaro Suzuki Sayuki Torii Maryam Zaid Atsushi Sato Hisatomi Arima Tomohiro Terada Katsuyuki Miura Hirotsugu Ueshima Association of Alcohol Consumption With Fat Deposition in a Community-Based Sample of Japanese Men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA) Journal of Epidemiology alcohol consumption visceral adipose tissue fat deposition anthropometric obesity indice |
| title | Association of Alcohol Consumption With Fat Deposition in a Community-Based Sample of Japanese Men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA) |
| title_full | Association of Alcohol Consumption With Fat Deposition in a Community-Based Sample of Japanese Men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA) |
| title_fullStr | Association of Alcohol Consumption With Fat Deposition in a Community-Based Sample of Japanese Men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA) |
| title_full_unstemmed | Association of Alcohol Consumption With Fat Deposition in a Community-Based Sample of Japanese Men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA) |
| title_short | Association of Alcohol Consumption With Fat Deposition in a Community-Based Sample of Japanese Men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA) |
| title_sort | association of alcohol consumption with fat deposition in a community based sample of japanese men the shiga epidemiological study of subclinical atherosclerosis sessa |
| topic | alcohol consumption visceral adipose tissue fat deposition anthropometric obesity indice |
| url | https://www.jstage.jst.go.jp/article/jea/29/6/29_JE20170191/_pdf |
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