A biophysically detailed computational model of urinary bladder small DRG neuron soma.
Bladder small DRG neurons, which are putative nociceptors pivotal to urinary bladder function, express more than a dozen different ionic membrane mechanisms: ion channels, pumps and exchangers. Small-conductance Ca2+-activated K+ (SKCa) channels which were earlier thought to be gated solely by intra...
Main Authors: | Darshan Mandge, Rohit Manchanda |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-07-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC6066259?pdf=render |
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