P464: PULSE DOSING OF POTENT AND SELECTIVE HETEROBIFUNCTIONAL MDM2 DEGRADER KT-253 DRIVES TUMOR REGRESSION AND DEMONSTRATES DIFFERENTIATED PHARMACOLOGY COMPARED TO P53/MDM2 SMALL MOLECULE INHIBITORS. - Stefanie Schalm; Yogesh Chutake; Susanne Breitkopf; Michele Mayo; Nancy Dumont; Dapeng Chen; Vaishali Dixit; Rahul Karnik; Alice Mcdonald; Jessica Filiatrault; William Proctor; Frank Qi; et al. (HemaSphere, 2023)