Chemokines and Their Role in Parasitic Diseases
Chemotactic cytokines (chemokines), the intercellular mediators, produced and released by a wide variety of cell types, are a group of small secreted proteins (8–10 KDa), which mediate host response to invading organisms (viruses, bacteria, parasites), trauma or tumor. The trafficking, recruiting an...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2004-05-01
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| Series: | European Journal of Inflammation |
| Online Access: | https://doi.org/10.1177/1721727X0400200201 |
| _version_ | 1818115320138694656 |
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| author | S. Frydas E. Karagouni E. Papadopoulos M. Hatzistilianou S. Pappas N. Papaioannou |
| author_facet | S. Frydas E. Karagouni E. Papadopoulos M. Hatzistilianou S. Pappas N. Papaioannou |
| author_sort | S. Frydas |
| collection | DOAJ |
| description | Chemotactic cytokines (chemokines), the intercellular mediators, produced and released by a wide variety of cell types, are a group of small secreted proteins (8–10 KDa), which mediate host response to invading organisms (viruses, bacteria, parasites), trauma or tumor. The trafficking, recruiting and recirculation of leukocytes, which is essential in acute and chronic inflammation is controlled by chemokines. This review introduces the three supergene families of chemokines (CXC, CC and C), with emphasis on their adhesion mechanism, biological effects, regulation of expression and critical role in different disease states in humans and in animal models with parasitic diseases. |
| first_indexed | 2024-12-11T04:04:45Z |
| format | Article |
| id | doaj.art-fcabb6db1a78479ca4bf1a12a1770a43 |
| institution | Directory Open Access Journal |
| issn | 1721-727X |
| language | English |
| last_indexed | 2024-12-11T04:04:45Z |
| publishDate | 2004-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | European Journal of Inflammation |
| spelling | doaj.art-fcabb6db1a78479ca4bf1a12a1770a432022-12-22T01:21:32ZengSAGE PublishingEuropean Journal of Inflammation1721-727X2004-05-01210.1177/1721727X0400200201Chemokines and Their Role in Parasitic DiseasesS. FrydasE. Karagouni0E. PapadopoulosM. Hatzistilianou1S. Pappas2N. Papaioannou3 Laboratory of Parasitology, Hellenic Pasteur Institute, Athens 2 Department of Pediatrics, Aristotle University of Thessaloniki, Thessaloniki 2 Department of Pediatrics, Aristotle University of Thessaloniki, Thessaloniki Department of Pathology, Aristotle University of Thessaloniki, Thessaloniki, GreeceChemotactic cytokines (chemokines), the intercellular mediators, produced and released by a wide variety of cell types, are a group of small secreted proteins (8–10 KDa), which mediate host response to invading organisms (viruses, bacteria, parasites), trauma or tumor. The trafficking, recruiting and recirculation of leukocytes, which is essential in acute and chronic inflammation is controlled by chemokines. This review introduces the three supergene families of chemokines (CXC, CC and C), with emphasis on their adhesion mechanism, biological effects, regulation of expression and critical role in different disease states in humans and in animal models with parasitic diseases.https://doi.org/10.1177/1721727X0400200201 |
| spellingShingle | S. Frydas E. Karagouni E. Papadopoulos M. Hatzistilianou S. Pappas N. Papaioannou Chemokines and Their Role in Parasitic Diseases European Journal of Inflammation |
| title | Chemokines and Their Role in Parasitic Diseases |
| title_full | Chemokines and Their Role in Parasitic Diseases |
| title_fullStr | Chemokines and Their Role in Parasitic Diseases |
| title_full_unstemmed | Chemokines and Their Role in Parasitic Diseases |
| title_short | Chemokines and Their Role in Parasitic Diseases |
| title_sort | chemokines and their role in parasitic diseases |
| url | https://doi.org/10.1177/1721727X0400200201 |
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