Assessing the change of anisometropia in unilateral myopic children receiving monocular orthokeratology treatment
Background: This study aimed at comparing the inter-eye axial elongation difference in order to evaluate the change of anisometropia in unilateral myopic children wearing monocular orthokeratology (Ortho-K) lens. Methods: In this retrospective cohort study, we recruited monocular myopic subjects tre...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2019-07-01
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| Series: | Journal of the Formosan Medical Association |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664618306508 |
| _version_ | 1818381060308729856 |
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| author | Wei-Shan Tsai Jen-Hung Wang Yuan-Chieh Lee Cheng-Jen Chiu |
| author_facet | Wei-Shan Tsai Jen-Hung Wang Yuan-Chieh Lee Cheng-Jen Chiu |
| author_sort | Wei-Shan Tsai |
| collection | DOAJ |
| description | Background: This study aimed at comparing the inter-eye axial elongation difference in order to evaluate the change of anisometropia in unilateral myopic children wearing monocular orthokeratology (Ortho-K) lens. Methods: In this retrospective cohort study, we recruited monocular myopic subjects treated with monocular Ortho-K lens from May 2012 to January 2017. The axial length (AL) of both eyes was recorded, and we calculated the AL difference as our primary outcome, to evaluate myopia progression. High anisometropia was defined as anisometropia more than 2.50D. The generalized estimating equations (GEE) model was used to assess the related risk factors. Results: A total number of 31 unilateral myopic patients were identified. The initial wearing age of the subjects was 12.32+/−3.07 years. In myopic eyes, the initial spherical equivalent was −2.73+/−0.95 diopter (D). The mean follow-up duration was 2.01+/−1.48 years. A significant reduction in the AL difference was found, from 0.83+/−0.45 millimeters at the baseline to 0.59+/−0.49 millimeters at 24 months (P = 0.039). Besides, after wearing Ortho-K lens for a long term, high anisometropic wearers showed more AL difference reduction than low anisometropic wearers in unilateral myopic children (P=0.002). Conclusion: This study demonstrated that the myopic eyes in unilateral myopic children had less AL growth than the companion emmetropic eyes when treated with monocular Ortho-K lenses. Wearing Ortho-K lens for a long time would present a more significant AL difference reduction in high anisometropic children. Keywords: Anisometropia, Axial length, Myopia control, Orthokeratology, Unilateral myopia |
| first_indexed | 2024-12-14T02:28:34Z |
| format | Article |
| id | doaj.art-fcae69380ad641dcb80f7077379025de |
| institution | Directory Open Access Journal |
| issn | 0929-6646 |
| language | English |
| last_indexed | 2024-12-14T02:28:34Z |
| publishDate | 2019-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of the Formosan Medical Association |
| spelling | doaj.art-fcae69380ad641dcb80f7077379025de2022-12-21T23:20:19ZengElsevierJournal of the Formosan Medical Association0929-66462019-07-01118711221128Assessing the change of anisometropia in unilateral myopic children receiving monocular orthokeratology treatmentWei-Shan Tsai0Jen-Hung Wang1Yuan-Chieh Lee2Cheng-Jen Chiu3Department of Ophthalmology, Buddhist Tzu Chi General Hospital, Hualien, TaiwanDepartment of Medical Research, Buddhist Tzu Chi General Hospital, Hualien, TaiwanDepartment of Ophthalmology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan; Department of Ophthalmology and Visual Science, Tzu Chi University, Hualien, Taiwan; Institute of Medical Science, Tzu Chi University, Hualien, Taiwan; Department of Ophthalmology, National Taiwan University Hospital, Taipei, TaiwanDepartment of Ophthalmology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan; Department of Ophthalmology and Visual Science, Tzu Chi University, Hualien, Taiwan; Corresponding author. Department of Ophthalmology, Buddhist Tzu Chi General Hospital, No. 707, Sec. 3, Zhong Yong Road, Hualien, 97002, Taiwan. Fax: +886 3 857 7161.Background: This study aimed at comparing the inter-eye axial elongation difference in order to evaluate the change of anisometropia in unilateral myopic children wearing monocular orthokeratology (Ortho-K) lens. Methods: In this retrospective cohort study, we recruited monocular myopic subjects treated with monocular Ortho-K lens from May 2012 to January 2017. The axial length (AL) of both eyes was recorded, and we calculated the AL difference as our primary outcome, to evaluate myopia progression. High anisometropia was defined as anisometropia more than 2.50D. The generalized estimating equations (GEE) model was used to assess the related risk factors. Results: A total number of 31 unilateral myopic patients were identified. The initial wearing age of the subjects was 12.32+/−3.07 years. In myopic eyes, the initial spherical equivalent was −2.73+/−0.95 diopter (D). The mean follow-up duration was 2.01+/−1.48 years. A significant reduction in the AL difference was found, from 0.83+/−0.45 millimeters at the baseline to 0.59+/−0.49 millimeters at 24 months (P = 0.039). Besides, after wearing Ortho-K lens for a long term, high anisometropic wearers showed more AL difference reduction than low anisometropic wearers in unilateral myopic children (P=0.002). Conclusion: This study demonstrated that the myopic eyes in unilateral myopic children had less AL growth than the companion emmetropic eyes when treated with monocular Ortho-K lenses. Wearing Ortho-K lens for a long time would present a more significant AL difference reduction in high anisometropic children. Keywords: Anisometropia, Axial length, Myopia control, Orthokeratology, Unilateral myopiahttp://www.sciencedirect.com/science/article/pii/S0929664618306508 |
| spellingShingle | Wei-Shan Tsai Jen-Hung Wang Yuan-Chieh Lee Cheng-Jen Chiu Assessing the change of anisometropia in unilateral myopic children receiving monocular orthokeratology treatment Journal of the Formosan Medical Association |
| title | Assessing the change of anisometropia in unilateral myopic children receiving monocular orthokeratology treatment |
| title_full | Assessing the change of anisometropia in unilateral myopic children receiving monocular orthokeratology treatment |
| title_fullStr | Assessing the change of anisometropia in unilateral myopic children receiving monocular orthokeratology treatment |
| title_full_unstemmed | Assessing the change of anisometropia in unilateral myopic children receiving monocular orthokeratology treatment |
| title_short | Assessing the change of anisometropia in unilateral myopic children receiving monocular orthokeratology treatment |
| title_sort | assessing the change of anisometropia in unilateral myopic children receiving monocular orthokeratology treatment |
| url | http://www.sciencedirect.com/science/article/pii/S0929664618306508 |
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