Ribosome profiling reveals translational regulation of mammalian cells in response to hypoxic stress

Ribosome profiling reveals translational regulation of mammalian cells in response to hypoxic stress

Abstract Background Retinal pigment epithelium (RPE) cells transfer oxygen and nutrients from choroid to the neural retina. Reduced oxygen to RPE perturbs development and functions of blood vessels in retina. Previous efforts of genome-wide studies have been largely focused on transcriptional change...

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Bibliographic Details
Main Authors: Zhiwen Jiang, Jiaqi Yang, Aimei Dai, Yuming Wang, Wei Li, Zhi Xie
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Genomics
Subjects:
Hypoxia
Ribosome profiling
Translation efficiency
Loading ratio
Upstream open reading frame
Online Access:http://link.springer.com/article/10.1186/s12864-017-3996-8

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