In vivo antimalarial effect of 1-hydroxy-5,6,7-trimethoxyxanthone isolated from Mammea siamensis T. Anders. flowers: pharmacokinetic and acute toxicity studies

In vivo antimalarial effect of 1-hydroxy-5,6,7-trimethoxyxanthone isolated from Mammea siamensis T. Anders. flowers: pharmacokinetic and acute toxicity studies

Abstract Background The potent antiplasmodial activity of 1-hydroxy-5,6,7-trimethoxyxanthone (HTX), isolated from Mammea siamensis T. Anders. flowers, has previously been demonstrated in vitro. However, its in vivo activity has not been reported. Therefore, this study aimed to investigate the antima...

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Bibliographic Details
Main Authors: Prapaporn Chaniad, Arnon Chukaew, Prasit Na-ek, Gorawit Yusakul, Litavadee Chuaboon, Arisara Phuwajaroanpong, Walaiporn Plirat, Atthaphon Konyanee, Abdi Wira Septama, Chuchard Punsawad
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Antimalarial activity
Mammea siamensis
Pharmacokinetic
1-Hydroxy-5,6,7-trimethoxyxanthone
Online Access:https://doi.org/10.1186/s12906-024-04427-z

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