Herba Patriniae and its component Isovitexin show anti-colorectal cancer effects by inducing apoptosis and cell-cycle arrest via p53 activation

Herba Patriniae and its component Isovitexin show anti-colorectal cancer effects by inducing apoptosis and cell-cycle arrest via p53 activation

Colorectal cancer (CRC) is the most prevalent cancer of the digestive tract. Herba Patriniae (also known as Bai Jiang Cao, HP) have been widely used to manage diarrhea, ulcerative colitis, and several cancers, including CRC. Nonetheless, the molecular mechanisms underlying the pharmacological action...

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Bibliographic Details
Main Authors: Jinxiao Li, Luorui Shang, Fangyuan Zhou, Shuhan Wang, Na Liu, Minfeng Zhou, Qifeng Lin, Mengqi Zhang, Yuju Cai, Guo Chen, Shenglan Yang
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Herba Patriniae，Isovitexin
Colorectal Cancer，p53 pathway，Apoptosis；Cell Cycle
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223014889

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http://www.sciencedirect.com/science/article/pii/S0753332223014889

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