Fanconi anemia pathway regulation by FANCI in prostate cancer

Fanconi anemia pathway regulation by FANCI in prostate cancer

Prostate cancer is one of the leading causes of death among men worldwide, and thus, research on the genetic factors enabling the formation of treatment-resistant cancer cells is crucial for improving patient outcomes. Here, we report a cell line-specific dependence on FANCI and related signaling pa...

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Bibliographic Details
Main Authors: Heidi Kaljunen, Sinja Taavitsainen, Roosa Kaarijärvi, Eerika Takala, Ville Paakinaho, Matti Nykter, G. Steven Bova, Kirsi Ketola
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Oncology
Subjects:
prostate
cancer
treatment resistance
DNA damage
carboplatin
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1260826/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1260826/full

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