Evaluation of the safety and efficacy of ultrasound-guided percutaneous radiofrequency ablation for hepatocellular carcinoma and liver metastases adjacent to the gallbladder
AbstractObjective To evaluate the safety and efficacy of ultrasound-guided percutaneous radiofrequency ablation (RFA) in patients with hepatocellular carcinoma (HCC) and liver metastases adjacent to the gallbladder (GB).Materials and methods A total of 113 patients with 118 liver lesions (63 HCC les...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2023-12-01
|
| Series: | International Journal of Hyperthermia |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/02656736.2023.2182748 |
| _version_ | 1797374264710529024 |
|---|---|
| author | Yuanfeng Meng Binbin Jiang Kun Yan Song Wang Zhongyi Zhang Luzeng Chen Wei Wu Wei Yang |
| author_facet | Yuanfeng Meng Binbin Jiang Kun Yan Song Wang Zhongyi Zhang Luzeng Chen Wei Wu Wei Yang |
| author_sort | Yuanfeng Meng |
| collection | DOAJ |
| description | AbstractObjective To evaluate the safety and efficacy of ultrasound-guided percutaneous radiofrequency ablation (RFA) in patients with hepatocellular carcinoma (HCC) and liver metastases adjacent to the gallbladder (GB).Materials and methods A total of 113 patients with 118 liver lesions (63 HCC lesions and 55 liver metastases) adjacent to the gallbladder underwent RFA between March 2011 and June 2019. Gallbladder-related complications and technique effectiveness rates were evaluated based on the classification of liver tumors and the distance between the lesion and the gallbladder.Results Gallbladder-related complications were observed in 13 patients. Among the patients with HCC, there was no significant difference between the ≤0.5 cm and >0.5 cm groups (p = .282). However, among the patients with liver metastases, the incidence of gallbladder-related complications in the ≤0.5 cm group was significantly higher than that in the >0.5 cm group (p = .025). The overall incidence of complications was significantly higher in the ≤0.5 cm group than in the >0.5 cm group (p = .020). Among the patients with lesions ≤3 cm, the technical effectiveness rate in the HCC group was significantly higher than in the liver metastasis group (p = .036).Conclusion RFA is a safe and effective treatment option for liver tumors adjacent to the gallbladder. Patients with lesions ≤0.5 cm from the gallbladder had higher gallbladder-related complications, especially patients with liver metastases. Among patients with lesions ≤3 cm, RFA showed greater technical effectiveness for treating HCC than for treating liver metastases. |
| first_indexed | 2024-03-08T19:03:21Z |
| format | Article |
| id | doaj.art-fcb8479fee884a77b9314a2981d6065d |
| institution | Directory Open Access Journal |
| issn | 0265-6736 1464-5157 |
| language | English |
| last_indexed | 2024-03-08T19:03:21Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj.art-fcb8479fee884a77b9314a2981d6065d2023-12-28T04:15:43ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572023-12-0140110.1080/02656736.2023.2182748Evaluation of the safety and efficacy of ultrasound-guided percutaneous radiofrequency ablation for hepatocellular carcinoma and liver metastases adjacent to the gallbladderYuanfeng Meng0Binbin Jiang1Kun Yan2Song Wang3Zhongyi Zhang4Luzeng Chen5Wei Wu6Wei Yang7Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Department of Ultrasound, Peking University Cancer Hospital & Institute, Beijing, ChinaKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Department of Ultrasound, Peking University Cancer Hospital & Institute, Beijing, ChinaKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Department of Ultrasound, Peking University Cancer Hospital & Institute, Beijing, ChinaKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Department of Ultrasound, Peking University Cancer Hospital & Institute, Beijing, ChinaKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Department of Ultrasound, Peking University Cancer Hospital & Institute, Beijing, ChinaDepartment of Ultrasound, Peking University First Hospital, Beijing, ChinaKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Department of Ultrasound, Peking University Cancer Hospital & Institute, Beijing, ChinaKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Department of Ultrasound, Peking University Cancer Hospital & Institute, Beijing, ChinaAbstractObjective To evaluate the safety and efficacy of ultrasound-guided percutaneous radiofrequency ablation (RFA) in patients with hepatocellular carcinoma (HCC) and liver metastases adjacent to the gallbladder (GB).Materials and methods A total of 113 patients with 118 liver lesions (63 HCC lesions and 55 liver metastases) adjacent to the gallbladder underwent RFA between March 2011 and June 2019. Gallbladder-related complications and technique effectiveness rates were evaluated based on the classification of liver tumors and the distance between the lesion and the gallbladder.Results Gallbladder-related complications were observed in 13 patients. Among the patients with HCC, there was no significant difference between the ≤0.5 cm and >0.5 cm groups (p = .282). However, among the patients with liver metastases, the incidence of gallbladder-related complications in the ≤0.5 cm group was significantly higher than that in the >0.5 cm group (p = .025). The overall incidence of complications was significantly higher in the ≤0.5 cm group than in the >0.5 cm group (p = .020). Among the patients with lesions ≤3 cm, the technical effectiveness rate in the HCC group was significantly higher than in the liver metastasis group (p = .036).Conclusion RFA is a safe and effective treatment option for liver tumors adjacent to the gallbladder. Patients with lesions ≤0.5 cm from the gallbladder had higher gallbladder-related complications, especially patients with liver metastases. Among patients with lesions ≤3 cm, RFA showed greater technical effectiveness for treating HCC than for treating liver metastases.https://www.tandfonline.com/doi/10.1080/02656736.2023.2182748Hepatocellular carcinomaliver metastasesradiofrequency ablationgallbladdersafetyefficacy |
| spellingShingle | Yuanfeng Meng Binbin Jiang Kun Yan Song Wang Zhongyi Zhang Luzeng Chen Wei Wu Wei Yang Evaluation of the safety and efficacy of ultrasound-guided percutaneous radiofrequency ablation for hepatocellular carcinoma and liver metastases adjacent to the gallbladder International Journal of Hyperthermia Hepatocellular carcinoma liver metastases radiofrequency ablation gallbladder safety efficacy |
| title | Evaluation of the safety and efficacy of ultrasound-guided percutaneous radiofrequency ablation for hepatocellular carcinoma and liver metastases adjacent to the gallbladder |
| title_full | Evaluation of the safety and efficacy of ultrasound-guided percutaneous radiofrequency ablation for hepatocellular carcinoma and liver metastases adjacent to the gallbladder |
| title_fullStr | Evaluation of the safety and efficacy of ultrasound-guided percutaneous radiofrequency ablation for hepatocellular carcinoma and liver metastases adjacent to the gallbladder |
| title_full_unstemmed | Evaluation of the safety and efficacy of ultrasound-guided percutaneous radiofrequency ablation for hepatocellular carcinoma and liver metastases adjacent to the gallbladder |
| title_short | Evaluation of the safety and efficacy of ultrasound-guided percutaneous radiofrequency ablation for hepatocellular carcinoma and liver metastases adjacent to the gallbladder |
| title_sort | evaluation of the safety and efficacy of ultrasound guided percutaneous radiofrequency ablation for hepatocellular carcinoma and liver metastases adjacent to the gallbladder |
| topic | Hepatocellular carcinoma liver metastases radiofrequency ablation gallbladder safety efficacy |
| url | https://www.tandfonline.com/doi/10.1080/02656736.2023.2182748 |
| work_keys_str_mv | AT yuanfengmeng evaluationofthesafetyandefficacyofultrasoundguidedpercutaneousradiofrequencyablationforhepatocellularcarcinomaandlivermetastasesadjacenttothegallbladder AT binbinjiang evaluationofthesafetyandefficacyofultrasoundguidedpercutaneousradiofrequencyablationforhepatocellularcarcinomaandlivermetastasesadjacenttothegallbladder AT kunyan evaluationofthesafetyandefficacyofultrasoundguidedpercutaneousradiofrequencyablationforhepatocellularcarcinomaandlivermetastasesadjacenttothegallbladder AT songwang evaluationofthesafetyandefficacyofultrasoundguidedpercutaneousradiofrequencyablationforhepatocellularcarcinomaandlivermetastasesadjacenttothegallbladder AT zhongyizhang evaluationofthesafetyandefficacyofultrasoundguidedpercutaneousradiofrequencyablationforhepatocellularcarcinomaandlivermetastasesadjacenttothegallbladder AT luzengchen evaluationofthesafetyandefficacyofultrasoundguidedpercutaneousradiofrequencyablationforhepatocellularcarcinomaandlivermetastasesadjacenttothegallbladder AT weiwu evaluationofthesafetyandefficacyofultrasoundguidedpercutaneousradiofrequencyablationforhepatocellularcarcinomaandlivermetastasesadjacenttothegallbladder AT weiyang evaluationofthesafetyandefficacyofultrasoundguidedpercutaneousradiofrequencyablationforhepatocellularcarcinomaandlivermetastasesadjacenttothegallbladder |