Association between Cognitive Function and Depression with Human T-Cell Lymphotropic Virus 1 Seropositivity and Serointensity in UK Adults
Several viral, bacterial, and parasitic diseases have been associated with cognitive function and neuropsychiatric outcomes in humans, including human T-cell lymphotropic virus 1 (HTLV-1). In this study, we sought to further generalize previously reported associations of cognitive function and depre...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-10-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/10/11/1409 |
| _version_ | 1827675768282415104 |
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| author | Lance D. Erickson Dawson W. Hedges Bruce L. Brown Bradley Embley Shawn D. Gale |
| author_facet | Lance D. Erickson Dawson W. Hedges Bruce L. Brown Bradley Embley Shawn D. Gale |
| author_sort | Lance D. Erickson |
| collection | DOAJ |
| description | Several viral, bacterial, and parasitic diseases have been associated with cognitive function and neuropsychiatric outcomes in humans, including human T-cell lymphotropic virus 1 (HTLV-1). In this study, we sought to further generalize previously reported associations of cognitive function and depression with HTLV-1 seropositivity and serointensity using a community-based sample of adults aged approximately 40 to 70 years (mean = 55.3 years) from the United Kingdom. In this sample, the results of adjusted linear regression models showed no associations of HTLV-1 seropositivity or serointensity with reasoning, pairs-matching, or reaction-time cognitive tasks or with depression. In addition, neither age, sex, educational attainment, nor income moderated associations of HTLV-1 seropositivity or serointensity with cognitive function or depression. In this middle-aged to older middle-aged adult community sample, HTLV-1 seropositivity and serointensity do not appear to be associated with reasoning, pairs-matching, and reaction-time tasks or with depression. |
| first_indexed | 2024-03-10T05:10:30Z |
| format | Article |
| id | doaj.art-fcb89a2c667b4af88bea0c2bffe95b4b |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T05:10:30Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-fcb89a2c667b4af88bea0c2bffe95b4b2023-11-23T00:52:52ZengMDPI AGPathogens2076-08172021-10-011011140910.3390/pathogens10111409Association between Cognitive Function and Depression with Human T-Cell Lymphotropic Virus 1 Seropositivity and Serointensity in UK AdultsLance D. Erickson0Dawson W. Hedges1Bruce L. Brown2Bradley Embley3Shawn D. Gale4Department of Sociology, Brigham Young University, Provo, UT 84602, USADepartment of Psychology, Brigham Young University, Provo, UT 84602, USADepartment of Psychology, Brigham Young University, Provo, UT 84602, USAThe Neuroscience Center, Brigham Young University, Provo, UT 84602, USADepartment of Psychology, Brigham Young University, Provo, UT 84602, USASeveral viral, bacterial, and parasitic diseases have been associated with cognitive function and neuropsychiatric outcomes in humans, including human T-cell lymphotropic virus 1 (HTLV-1). In this study, we sought to further generalize previously reported associations of cognitive function and depression with HTLV-1 seropositivity and serointensity using a community-based sample of adults aged approximately 40 to 70 years (mean = 55.3 years) from the United Kingdom. In this sample, the results of adjusted linear regression models showed no associations of HTLV-1 seropositivity or serointensity with reasoning, pairs-matching, or reaction-time cognitive tasks or with depression. In addition, neither age, sex, educational attainment, nor income moderated associations of HTLV-1 seropositivity or serointensity with cognitive function or depression. In this middle-aged to older middle-aged adult community sample, HTLV-1 seropositivity and serointensity do not appear to be associated with reasoning, pairs-matching, and reaction-time tasks or with depression.https://www.mdpi.com/2076-0817/10/11/1409human T-cell lymphotropic virus 1HTLV-1cognitiondepressionUK Biobank |
| spellingShingle | Lance D. Erickson Dawson W. Hedges Bruce L. Brown Bradley Embley Shawn D. Gale Association between Cognitive Function and Depression with Human T-Cell Lymphotropic Virus 1 Seropositivity and Serointensity in UK Adults Pathogens human T-cell lymphotropic virus 1 HTLV-1 cognition depression UK Biobank |
| title | Association between Cognitive Function and Depression with Human T-Cell Lymphotropic Virus 1 Seropositivity and Serointensity in UK Adults |
| title_full | Association between Cognitive Function and Depression with Human T-Cell Lymphotropic Virus 1 Seropositivity and Serointensity in UK Adults |
| title_fullStr | Association between Cognitive Function and Depression with Human T-Cell Lymphotropic Virus 1 Seropositivity and Serointensity in UK Adults |
| title_full_unstemmed | Association between Cognitive Function and Depression with Human T-Cell Lymphotropic Virus 1 Seropositivity and Serointensity in UK Adults |
| title_short | Association between Cognitive Function and Depression with Human T-Cell Lymphotropic Virus 1 Seropositivity and Serointensity in UK Adults |
| title_sort | association between cognitive function and depression with human t cell lymphotropic virus 1 seropositivity and serointensity in uk adults |
| topic | human T-cell lymphotropic virus 1 HTLV-1 cognition depression UK Biobank |
| url | https://www.mdpi.com/2076-0817/10/11/1409 |
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