Oleuropein Improved Post Cerebral Stroke Cognitive Function by Promoting Histone Acetylation and Phosphorylation of cAMP Response Element-Binding Protein in MCAO Rats

Oleuropein Improved Post Cerebral Stroke Cognitive Function by Promoting Histone Acetylation and Phosphorylation of cAMP Response Element-Binding Protein in MCAO Rats

Background: Post-stroke cognitive impairment (PSCI) is commonest clinical disorder in which peripheral cholinergic activity is important. Oleuropein (OLP) is polyphenol is present in olive oil. Here we evaluated the effect of OLP in cognitive dysfunction rats in post cerebral stroke model. Methods:...

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Bibliographic Details
Main Authors: Yang Gao, Xiaojin Li, Rongjian Xu, Yan Guo, Haiyan Yin, Ruifeng Tan, Ze Qi, Guangzhe Liu, Jiahui Liang, Bailiu Ya
Format: Article
Language:English
Published: SAGE Publishing 2020-08-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325820950102

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