miR-6805-5p as a biomarker of cisplatin-induced nephrotoxicity in patients with head and neck cancer

miR-6805-5p as a biomarker of cisplatin-induced nephrotoxicity in patients with head and neck cancer

Introduction: The standard treatment for head and neck squamous cell carcinoma (HNSCC) is cisplatin chemoradiotherapy. One of the main treatment adverse reactions is nephrotoxicity, for which there is currently no adequate specific and sensitive biomarker. Thus, this study aimed to evaluate the use...

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Main Authors: Nadine De Godoy Torso, Julia Coelho França Quintanilha, Maria Aparecida Cursino, Eder De Carvalho Pincinato, Pía Loren, Luis A. Salazar, Carmen Silvia Passos Lima, Patricia Moriel
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
cisplatin
nephrotoxicity
acute kidney injury
biomarker
microRNA
miRNA
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1275238/full

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