Mechanism of inflammatory cancer-associated fibroblast-mediated drug resistance in colorectal cancer cells

Mechanism of inflammatory cancer-associated fibroblast-mediated drug resistance in colorectal cancer cells

Background and purpose: Colorectal cancer (CRC) is one of the common malignancies, but the mechanism by which it develops resistance to drug remains unclear. The tumor microenvironment (TME), especially cancer-associated fibroblast (CAF), plays an important role in the occurrence, development and dr...

Full description

Bibliographic Details
Main Author:	CAI Jialuo, ZHU Ruiqiu, LI Sen, CAO Yijun, HUANG Fang
Format:	Article
Language:	English
Published:	Editorial Office of China Oncology 2023-12-01
Series:	Zhongguo aizheng zazhi
Subjects:	\|colorectal cancer\|inflammatory cancer-associated fibroblasts\|drug resistance\|wnt/β-catenin signaling pathway
Online Access:	http://www.china-oncology.com/fileup/1007-3639/PDF/1703749953238-2122322508.pdf

Similar Items

WDR74 promotes proliferation and metastasis in colorectal cancer cells through regulating the Wnt/β-catenin signaling pathway
by: Cai Zhou, et al.
Published: (2021-09-01)

Transcriptional Regulation of Wnt/β-Catenin Pathway in Colorectal Cancer
by: Jia Bian, et al.
Published: (2020-09-01)

A Bioactive Compound from <i>Sanguisorba officinalis</i> L. Inhibits Cell Proliferation and Induces Cell Death in 5-Fluorouracil-Sensitive/Resistant Colorectal Cancer Cells
by: Weijia Zhang, et al.
Published: (2021-06-01)

A Novel Fibromodulin Antagonist Peptide RP4 Exerts Antitumor Effects on Colorectal Cancer
by: Ting Deng, et al.
Published: (2023-03-01)

The Wnt Signalling Pathway: A Tailored Target in Cancer
by: Malvina Koni, et al.
Published: (2020-10-01)

Ubiquitin-Specific Peptidase 22 Contributes to Colorectal Cancer Stemness and Chemoresistance via Wnt/β-Catenin Pathway
by: Shixiong Jiang, et al.
Published: (2018-04-01)

Cryptolepine Suppresses Colorectal Cancer Cell Proliferation, Stemness, and Metastatic Processes by Inhibiting WNT/β-Catenin Signaling
by: Jude Tetteh Quarshie, et al.
Published: (2023-07-01)

Molecular Mechanisms of the Antitumor Effects of Mesalazine and Its Preventive Potential in Colorectal Cancer
by: Joanna Słoka, et al.
Published: (2023-06-01)

Targeting Wnt Signaling for Gastrointestinal Cancer Therapy: Present and Evolving Views
by: Moon Jong Kim, et al.
Published: (2020-12-01)

Organ Specificity and Heterogeneity of Cancer-Associated Fibroblasts in Colorectal Cancer
by: Naoya Miyashita, et al.
Published: (2021-10-01)

The MYC 3′ Wnt-Responsive Element Drives Oncogenic MYC Expression in Human Colorectal Cancer Cells
by: Sherri A. Rennoll, et al.
Published: (2016-05-01)

A Tryptophan Metabolite, 8-Hydroxyquinaldic Acid, Exerts Antiproliferative and Anti-Migratory Effects on Colorectal Cancer Cells
by: Katarzyna Walczak, et al.
Published: (2020-04-01)

The Role of the C-Clamp in Wnt-Related Colorectal Cancers
by: Aditi J. Ravindranath, et al.
Published: (2016-08-01)

ACY1 Downregulation Enhances the Radiosensitivity of Cetuximab-Resistant Colorectal Cancer by Inactivating the Wnt/β-Catenin Signaling Pathway
by: Wulin Shan, et al.
Published: (2022-11-01)

Crosstalk between enteric serotonergic neurons and colorectal cancer stem cells to initiate colorectal tumorigenesis
by: Jiamei Jia, et al.
Published: (2022-11-01)

Analysis of molecular aberrations of Wnt pathway gladiators in colorectal cancer in the Kashmiri population
by: Sameer A, et al.
Published: (2011-07-01)

Cepharanthine suppresses APC-mutant colorectal cancers by down-regulating the expression of β-catenin
by: Guifeng Su, et al.
Published: (2024-02-01)

Modulatory Effect of Chlorogenic Acid and Coffee Extracts on Wnt/β-Catenin Pathway in Colorectal Cancer Cells
by: Hernán Villota, et al.
Published: (2022-11-01)

Clinical significancy of WNT pathway inhibition in various cancers
by: Patryk Rogaczewski, et al.
Published: (2022-11-01)

Crosstalk between PI3K/Akt and Wnt/β-catenin pathways promote colorectal cancer progression regardless of mutational status
by: Cassio Dejair Fleming-de-Moraes, et al.
Published: (2022-12-01)

The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis
by: Nydia Tejeda-Munoz, et al.
Published: (2023-10-01)

Huaier Regulates Oxaliplatin Resistance in Colorectal Cancer by Regulating Autophagy and Inhibiting the Wnt/β-catenin Signalling Pathway
by: Qi Feng, et al.
Published: (2024-01-01)

RGL2 Drives the Metastatic Progression of Colorectal Cancer via Preventing the Protein Degradation of β-Catenin and KRAS
by: Meng-Shun Sun, et al.
Published: (2021-04-01)

Liquidambaric lactone is a potent inhibitor of TRAF2 for cancer therapy
by: Hongyan Zhu, et al.
Published: (2023-06-01)

Tumoricidal properties of thymoquinone on human colorectal adenocarcinoma cells via the modulation of autophagy
by: Mohammad Saleh Moulana, et al.
Published: (2024-03-01)

GPER Agonist G1 Prevents Wnt-Induced <i>JUN</i> Upregulation in HT29 Colorectal Cancer Cells
by: Maria Abancens, et al.
Published: (2022-10-01)

Visinin‐like 1, a novel target gene of the Wnt/β‐catenin signaling pathway, is involved in apoptosis resistance in colorectal cancer
by: Hiroki Tage, et al.
Published: (2023-06-01)

Uncoupling p38α nuclear and cytoplasmic functions and identification of two p38α phosphorylation sites on β-catenin: implications for the Wnt signaling pathway in CRC models
by: Martina Lepore Signorile, et al.
Published: (2023-12-01)

β-catenin inhibitors in cancer therapeutics: intricacies and way forward
by: Arundhathi Dev, et al.
Published: (2023-12-01)

Structural Insight into TNIK Inhibition
by: Mutsuko Kukimoto-Niino, et al.
Published: (2022-10-01)

Natural compounds: Wnt pathway inhibitors with therapeutic potential in lung cancer
by: Xuetong Shen, et al.
Published: (2023-09-01)

Oncogenic Serine 45-Deleted β-Catenin Remains Susceptible to Wnt Stimulation and APC Regulation in Human Colonocytes
by: Taybor W. Parker, et al.
Published: (2020-07-01)

Advances of Wnt Signalling Pathway in Colorectal Cancer
by: Yaoyao Zhu, et al.
Published: (2023-01-01)

Astragalus membranaceus (Huangqi) and Rhizoma curcumae (Ezhu) decoction suppresses colorectal cancer via downregulation of Wnt5/β-Catenin signal
by: Yong Bian, et al.
Published: (2022-01-01)

Cancer-Associated Fibroblasts: The Origin, Biological Characteristics and Role in Cancer—A Glance on Colorectal Cancer
by: Charalampos Fotsitzoudis, et al.
Published: (2022-09-01)

The Hedgehog Inhibitor Cyclopamine Reduces β-Catenin-Tcf Transcriptional Activity, Induces E-Cadherin Expression, and Reduces Invasion in Colorectal Cancer Cells
by: David Qualtrough, et al.
Published: (2015-09-01)

Resistomycin Inhibits Wnt/β-Catenin Signaling to Induce the Apoptotic Death of Human Colorectal Cancer Cells
by: Yaoyao Zhu, et al.
Published: (2023-11-01)

Function and mechanism of exogenous AGR2 in colorectal cancer cells
by: Chao Zheng, et al.
Published: (2024-04-01)

Cancer-Associated Fibroblasts Are Key Determinants of Cancer Cell Invasion in the Earliest Stage of Colorectal CancerSummary
by: Hao Dang, et al.
Published: (2023-01-01)

A Comprehensive View on the Quercetin Impact on Colorectal Cancer
by: Andreea-Adriana Neamtu, et al.
Published: (2022-03-01)