The Role of lncRNA in the Development of Tumors, including Breast Cancer
Long noncoding RNAs (lncRNAs) are the largest groups of ribonucleic acids, but, despite the increasing amount of literature data, the least understood. Given the involvement of lncRNA in basic cellular processes, especially in the regulation of transcription, the role of these noncoding molecules se...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/22/16/8427 |
| _version_ | 1797523675702886400 |
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| author | Beata Smolarz Anna Zadrożna-Nowak Hanna Romanowicz |
| author_facet | Beata Smolarz Anna Zadrożna-Nowak Hanna Romanowicz |
| author_sort | Beata Smolarz |
| collection | DOAJ |
| description | Long noncoding RNAs (lncRNAs) are the largest groups of ribonucleic acids, but, despite the increasing amount of literature data, the least understood. Given the involvement of lncRNA in basic cellular processes, especially in the regulation of transcription, the role of these noncoding molecules seems to be of great importance for the proper functioning of the organism. Studies have shown a relationship between disturbed lncRNA expression and the pathogenesis of many diseases, including cancer. The present article presents a detailed review of the latest reports and data regarding the importance of lncRNA in the development of cancers, including breast carcinoma. |
| first_indexed | 2024-03-10T08:46:24Z |
| format | Article |
| id | doaj.art-fcc3e1524fb2400fb60831e12d1048be |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T08:46:24Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-fcc3e1524fb2400fb60831e12d1048be2023-11-22T07:54:52ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-08-012216842710.3390/ijms22168427The Role of lncRNA in the Development of Tumors, including Breast CancerBeata Smolarz0Anna Zadrożna-Nowak1Hanna Romanowicz2Laboratory of Cancer Genetics, Department of Pathology, Polish Mother’s Memorial Hospital Research Institute, Rzgowska 281/289, 93-338 Lodz, PolandDepartment of Chemotherapy, Copernicus Memorial Hospital, Medical University of Lodz, 93-513 Lodz, PolandLaboratory of Cancer Genetics, Department of Pathology, Polish Mother’s Memorial Hospital Research Institute, Rzgowska 281/289, 93-338 Lodz, PolandLong noncoding RNAs (lncRNAs) are the largest groups of ribonucleic acids, but, despite the increasing amount of literature data, the least understood. Given the involvement of lncRNA in basic cellular processes, especially in the regulation of transcription, the role of these noncoding molecules seems to be of great importance for the proper functioning of the organism. Studies have shown a relationship between disturbed lncRNA expression and the pathogenesis of many diseases, including cancer. The present article presents a detailed review of the latest reports and data regarding the importance of lncRNA in the development of cancers, including breast carcinoma.https://www.mdpi.com/1422-0067/22/16/8427tumorsbreast cancerlncRNAexpression |
| spellingShingle | Beata Smolarz Anna Zadrożna-Nowak Hanna Romanowicz The Role of lncRNA in the Development of Tumors, including Breast Cancer International Journal of Molecular Sciences tumors breast cancer lncRNA expression |
| title | The Role of lncRNA in the Development of Tumors, including Breast Cancer |
| title_full | The Role of lncRNA in the Development of Tumors, including Breast Cancer |
| title_fullStr | The Role of lncRNA in the Development of Tumors, including Breast Cancer |
| title_full_unstemmed | The Role of lncRNA in the Development of Tumors, including Breast Cancer |
| title_short | The Role of lncRNA in the Development of Tumors, including Breast Cancer |
| title_sort | role of lncrna in the development of tumors including breast cancer |
| topic | tumors breast cancer lncRNA expression |
| url | https://www.mdpi.com/1422-0067/22/16/8427 |
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