Baseline Cerebrospinal Fluid α-Synuclein in Parkinson’s Disease Is Associated with Disease Progression and Cognitive Decline

Baseline Cerebrospinal Fluid α-Synuclein in Parkinson’s Disease Is Associated with Disease Progression and Cognitive Decline

Biomarkers are increasingly recognized as tools in the diagnosis and prognosis of neurodegenerative diseases. No fluid biomarker for Parkinson’s disease (PD) has been established to date, but α-synuclein, a major component of Lewy bodies in PD and dementia with Lewy bodies (DLB), has become a promis...

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Bibliographic Details
Main Authors: Anna Emdina, Peter Hermann, Daniela Varges, Sabine Nuhn, Stefan Goebel, Timothy Bunck, Fabian Maass, Matthias Schmitz, Franc Llorens, Niels Kruse, Paul Lingor, Brit Mollenhauer, Inga Zerr
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Diagnostics
Subjects:
Parkinson’s disease
dementia
dementia with Lewy bodies
alpha-synuclein
biomarker
cerebrospinal fluid
Online Access:https://www.mdpi.com/2075-4418/12/5/1259

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https://www.mdpi.com/2075-4418/12/5/1259

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