Food Allergy Risk: A Comprehensive Review of Maternal Interventions for Food Allergy Prevention
Food allergy represents a global health problem impacting patients’ and caregivers’ quality of life and contributing to increased healthcare costs. Efforts to identify preventive measures starting from pregnancy have recently intensified. This review aims to provide an overview of the role of matern...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-04-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/16/7/1087 |
| _version_ | 1797212124825518080 |
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| author | Sara Manti Francesca Galletta Chiara Lucia Bencivenga Irene Bettini Angela Klain Elisabetta D’Addio Francesca Mori Amelia Licari Michele Miraglia del Giudice Cristiana Indolfi |
| author_facet | Sara Manti Francesca Galletta Chiara Lucia Bencivenga Irene Bettini Angela Klain Elisabetta D’Addio Francesca Mori Amelia Licari Michele Miraglia del Giudice Cristiana Indolfi |
| author_sort | Sara Manti |
| collection | DOAJ |
| description | Food allergy represents a global health problem impacting patients’ and caregivers’ quality of life and contributing to increased healthcare costs. Efforts to identify preventive measures starting from pregnancy have recently intensified. This review aims to provide an overview of the role of maternal factors in food allergy prevention. Several studies indicate that avoiding food allergens during pregnancy does not reduce the risk of developing food allergies. International guidelines unanimously discourage avoidance diets due to potential adverse effects on essential nutrient intake and overall health for both women and children. Research on probiotics and prebiotics during pregnancy as preventive measures is promising, though evidence remains limited. Consequently, guidelines lack specific recommendations for their use in preventing food allergies. Similarly, given the absence of conclusive evidence, it is not possible to formulate definitive conclusions on the supplementation of vitamins, omega-3 fatty acids (<i>n</i>-3 PUFAs), and other antioxidant substances. A combination of maternal interventions, breastfeeding, and early introduction of foods to infants can reduce the risk of food allergies in the child. Further studies are needed to clarify the interaction between genetics, immunological pathways, and environmental factors |
| first_indexed | 2024-04-24T10:37:24Z |
| format | Article |
| id | doaj.art-fcc76343b30549169ed080939a0b260b |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-04-24T10:37:24Z |
| publishDate | 2024-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-fcc76343b30549169ed080939a0b260b2024-04-12T13:24:34ZengMDPI AGNutrients2072-66432024-04-01167108710.3390/nu16071087Food Allergy Risk: A Comprehensive Review of Maternal Interventions for Food Allergy PreventionSara Manti0Francesca Galletta1Chiara Lucia Bencivenga2Irene Bettini3Angela Klain4Elisabetta D’Addio5Francesca Mori6Amelia Licari7Michele Miraglia del Giudice8Cristiana Indolfi9Pediatric Unit, Department of Human Pathology in Adult and Developmental Age ‘Gaetano Barresi’, University of Messina, 98124 Messina, ItalyPediatric Unit, Department of Human Pathology in Adult and Developmental Age ‘Gaetano Barresi’, University of Messina, 98124 Messina, ItalyDepartment of Woman, Child and of General and Specialized Surgery, University of Campania ‘Luigi Vanvitelli’, 80138 Naples, ItalyPediatric Unit, IRCCS Azienda Ospedaliera-Universitaria di Bologna, 40138 Bologna, ItalyDepartment of Woman, Child and of General and Specialized Surgery, University of Campania ‘Luigi Vanvitelli’, 80138 Naples, ItalyDepartment of Woman, Child and of General and Specialized Surgery, University of Campania ‘Luigi Vanvitelli’, 80138 Naples, ItalyAllergy Unit, Meyer Children’s Hospital, IRCCS, 50139 Florence, ItalyDepartment of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, 27100 Pavia, ItalyDepartment of Woman, Child and of General and Specialized Surgery, University of Campania ‘Luigi Vanvitelli’, 80138 Naples, ItalyDepartment of Woman, Child and of General and Specialized Surgery, University of Campania ‘Luigi Vanvitelli’, 80138 Naples, ItalyFood allergy represents a global health problem impacting patients’ and caregivers’ quality of life and contributing to increased healthcare costs. Efforts to identify preventive measures starting from pregnancy have recently intensified. This review aims to provide an overview of the role of maternal factors in food allergy prevention. Several studies indicate that avoiding food allergens during pregnancy does not reduce the risk of developing food allergies. International guidelines unanimously discourage avoidance diets due to potential adverse effects on essential nutrient intake and overall health for both women and children. Research on probiotics and prebiotics during pregnancy as preventive measures is promising, though evidence remains limited. Consequently, guidelines lack specific recommendations for their use in preventing food allergies. Similarly, given the absence of conclusive evidence, it is not possible to formulate definitive conclusions on the supplementation of vitamins, omega-3 fatty acids (<i>n</i>-3 PUFAs), and other antioxidant substances. A combination of maternal interventions, breastfeeding, and early introduction of foods to infants can reduce the risk of food allergies in the child. Further studies are needed to clarify the interaction between genetics, immunological pathways, and environmental factorshttps://www.mdpi.com/2072-6643/16/7/1087childrenevidencefood allergypreventionpregnancy |
| spellingShingle | Sara Manti Francesca Galletta Chiara Lucia Bencivenga Irene Bettini Angela Klain Elisabetta D’Addio Francesca Mori Amelia Licari Michele Miraglia del Giudice Cristiana Indolfi Food Allergy Risk: A Comprehensive Review of Maternal Interventions for Food Allergy Prevention Nutrients children evidence food allergy prevention pregnancy |
| title | Food Allergy Risk: A Comprehensive Review of Maternal Interventions for Food Allergy Prevention |
| title_full | Food Allergy Risk: A Comprehensive Review of Maternal Interventions for Food Allergy Prevention |
| title_fullStr | Food Allergy Risk: A Comprehensive Review of Maternal Interventions for Food Allergy Prevention |
| title_full_unstemmed | Food Allergy Risk: A Comprehensive Review of Maternal Interventions for Food Allergy Prevention |
| title_short | Food Allergy Risk: A Comprehensive Review of Maternal Interventions for Food Allergy Prevention |
| title_sort | food allergy risk a comprehensive review of maternal interventions for food allergy prevention |
| topic | children evidence food allergy prevention pregnancy |
| url | https://www.mdpi.com/2072-6643/16/7/1087 |
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