Expression of the RNA helicase DDX3 and the hypoxia response in breast cancer.

<h4>Aims</h4>DDX3 is an RNA helicase that has antiapoptotic properties, and promotes proliferation and transformation. In addition, DDX3 was shown to be a direct downstream target of HIF-1α (the master regulatory of the hypoxia response) in breast cancer cell lines. However, the relation...

Полное описание

Библиографические подробности
Главные авторы: Guus M Bol, Venu Raman, Petra van der Groep, Jeroen F Vermeulen, Arvind H Patel, Elsken van der Wall, Paul J van Diest
Формат: Статья
Язык:English
Опубликовано: Public Library of Science (PLoS) 2013-01-01
Серии:PLoS ONE
Online-ссылка:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23696831/pdf/?tool=EBI