Using an Aluminum Hydroxide–Chitosan Matrix Increased the Vaccine Potential and Immune Response of Mice against Multi-Drug-Resistant <i>Acinetobacter baumannii</i>

Using an Aluminum Hydroxide–Chitosan Matrix Increased the Vaccine Potential and Immune Response of Mice against Multi-Drug-Resistant <i>Acinetobacter baumannii</i>

<i>Acinetobacter baumannii</i> is a Gram-negative, immobile, aerobic nosocomial opportunistic coccobacillus that causes pneumonia, septicemia, and urinary tract infections in immunosuppressed patients. There are no commercially available alternative antimicrobials, and multi-drug resista...

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Main Authors: Túllio T. Deusdará, Mellanie K. C. Félix, Helio de S. Brito, Edson W. S. Cangussu, Wellington de S. Moura, Benedito Albuquerque, Marcos G. Silva, Gil R. dos Santos, Paula B. de Morais, Elizangela F. da Silva, Yury O. Chaves, Luis Andre M. Mariúba, Paulo A. Nogueira, Spartaco Astolfi-Filho, Enedina N. Assunção, Sabrina Epiphanio, Claudio R. F. Marinho, Igor V. Brandi, Kelvinson F. Viana, Eugenio E. Oliveira, Alex Sander R. Cangussu
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Vaccines
Subjects:
multi-drug-resistant
<i>Acinetobacter baumannii</i>
immunosuppression model
inactivated whole-cell vaccine
Online Access:https://www.mdpi.com/2076-393X/11/3/669

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