Gastrointestinal carcinoid tumors Tumores carcinoides digestivos
Objective: carcinoid tumors (CTs) represent the commonest neuroendocrine tumors. Those in the gastrointestinal tract are diagnosed in surgical specimens, clinically, and using imaging techniques (endoscopy, echoendoscopy, CT, Octreoscan, etc.). The goal of this retrospective study was to review a pe...
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| Format: | Article |
| Language: | English |
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Aran Ediciones
2010-09-01
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| Series: | Revista Espanola de Enfermedades Digestivas |
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| Online Access: | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082010000900004 |
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| author | M. J. Varas Lorenzo F. Muñoz Agel J. C. Espinós Pérez M. Bardají Bofill |
| author_facet | M. J. Varas Lorenzo F. Muñoz Agel J. C. Espinós Pérez M. Bardají Bofill |
| author_sort | M. J. Varas Lorenzo |
| collection | DOAJ |
| description | Objective: carcinoid tumors (CTs) represent the commonest neuroendocrine tumors. Those in the gastrointestinal tract are diagnosed in surgical specimens, clinically, and using imaging techniques (endoscopy, echoendoscopy, CT, Octreoscan, etc.). The goal of this retrospective study was to review a personal series of gastrointestinal carcinoid tumors, and to compare it to those in the literature. Patients and methods: the medical records of 40 Caucasian patients with over 50 gastrointestinal carcinoid tumors (including multiple cases) who were seen for a period of 16 years (1994-2009) were reviewed. Results: mean age at presentation was 52 years, 50% were females, and mean tumor size was 9.9 mm. Most were gastroduodenal (42.5%) or rectal (30%), and were treated endoscopically. Metastases and carcinoid syndrome (CS) were seen in 5% of patients. Survival at study endpoint was 85%. Conclusions: age and gender were consistent with the literature. There was an increase in gastroduodenal (multifocal) and rectal carcinoids, likely because the series was essentially endoscopical in nature (bias). There was a lower rate of CS and higher survival, likely due to earlier diagnosis and treatment.<br>Objetivo: los tumores carcinoides (TC) son los tumores neuroendocrinos más frecuentes. Los digestivos se diagnostican en las piezas quirúrgicas, en la clínica, y mediante los métodos de imagen (endoscopia, ecoendoscopia, TAC y Octreoscan, etc.). El objetivo de este trabajo retrospectivo fue revisar una serie personal de tumores carcinoides digestivos y compararla con la literatura. Pacientes y métodos: se revisaron las historias clínicas de 40 pacientes de raza blanca con más de 50 tumores carcinoides digestivos, algunos múltiples, observados durante 16 años (1994-2009). Resultados: la edad media de presentación fue 52 años, 50% mujeres, con un tamaño medio del tumor de 9,9 mm. La mayoría eran gastroduodenales (42,5%) y rectales (30%) y fueron tratados por vía endoscópica. Las metástasis y el síndrome carcinoide (SC) se observó en un 5% de los casos. La supervivencia en el momento de cerrar el estudio era del 85%. Conclusiones: la edad y el sexo fueron similares a lo descrito en la literatura. Hubo un aumento de los carcinoides gastroduodenales (multifocales) y rectales, probablemente porque la serie era fundamentalmente endoscópica (sesgo). Se observó una disminución de la aparición SC y un aumento de la supervivencia probablemente por un diagnóstico y tratamiento más precoz. |
| first_indexed | 2024-12-19T09:28:31Z |
| format | Article |
| id | doaj.art-fcd1c261dfe246c7995d6037f459a067 |
| institution | Directory Open Access Journal |
| issn | 1130-0108 |
| language | English |
| last_indexed | 2024-12-19T09:28:31Z |
| publishDate | 2010-09-01 |
| publisher | Aran Ediciones |
| record_format | Article |
| series | Revista Espanola de Enfermedades Digestivas |
| spelling | doaj.art-fcd1c261dfe246c7995d6037f459a0672022-12-21T20:27:44ZengAran EdicionesRevista Espanola de Enfermedades Digestivas1130-01082010-09-011029533537Gastrointestinal carcinoid tumors Tumores carcinoides digestivosM. J. Varas LorenzoF. Muñoz AgelJ. C. Espinós PérezM. Bardají BofillObjective: carcinoid tumors (CTs) represent the commonest neuroendocrine tumors. Those in the gastrointestinal tract are diagnosed in surgical specimens, clinically, and using imaging techniques (endoscopy, echoendoscopy, CT, Octreoscan, etc.). The goal of this retrospective study was to review a personal series of gastrointestinal carcinoid tumors, and to compare it to those in the literature. Patients and methods: the medical records of 40 Caucasian patients with over 50 gastrointestinal carcinoid tumors (including multiple cases) who were seen for a period of 16 years (1994-2009) were reviewed. Results: mean age at presentation was 52 years, 50% were females, and mean tumor size was 9.9 mm. Most were gastroduodenal (42.5%) or rectal (30%), and were treated endoscopically. Metastases and carcinoid syndrome (CS) were seen in 5% of patients. Survival at study endpoint was 85%. Conclusions: age and gender were consistent with the literature. There was an increase in gastroduodenal (multifocal) and rectal carcinoids, likely because the series was essentially endoscopical in nature (bias). There was a lower rate of CS and higher survival, likely due to earlier diagnosis and treatment.<br>Objetivo: los tumores carcinoides (TC) son los tumores neuroendocrinos más frecuentes. Los digestivos se diagnostican en las piezas quirúrgicas, en la clínica, y mediante los métodos de imagen (endoscopia, ecoendoscopia, TAC y Octreoscan, etc.). El objetivo de este trabajo retrospectivo fue revisar una serie personal de tumores carcinoides digestivos y compararla con la literatura. Pacientes y métodos: se revisaron las historias clínicas de 40 pacientes de raza blanca con más de 50 tumores carcinoides digestivos, algunos múltiples, observados durante 16 años (1994-2009). Resultados: la edad media de presentación fue 52 años, 50% mujeres, con un tamaño medio del tumor de 9,9 mm. La mayoría eran gastroduodenales (42,5%) y rectales (30%) y fueron tratados por vía endoscópica. Las metástasis y el síndrome carcinoide (SC) se observó en un 5% de los casos. La supervivencia en el momento de cerrar el estudio era del 85%. Conclusiones: la edad y el sexo fueron similares a lo descrito en la literatura. Hubo un aumento de los carcinoides gastroduodenales (multifocales) y rectales, probablemente porque la serie era fundamentalmente endoscópica (sesgo). Se observó una disminución de la aparición SC y un aumento de la supervivencia probablemente por un diagnóstico y tratamiento más precoz.http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082010000900004Tumores carcinoides digestivosTumores neuroendocrinosSíndrome carcinoideGastrointestinal carcinoid tumorsNeuroendocrine tumorsCarcinoid syndrome |
| spellingShingle | M. J. Varas Lorenzo F. Muñoz Agel J. C. Espinós Pérez M. Bardají Bofill Gastrointestinal carcinoid tumors Tumores carcinoides digestivos Revista Espanola de Enfermedades Digestivas Tumores carcinoides digestivos Tumores neuroendocrinos Síndrome carcinoide Gastrointestinal carcinoid tumors Neuroendocrine tumors Carcinoid syndrome |
| title | Gastrointestinal carcinoid tumors Tumores carcinoides digestivos |
| title_full | Gastrointestinal carcinoid tumors Tumores carcinoides digestivos |
| title_fullStr | Gastrointestinal carcinoid tumors Tumores carcinoides digestivos |
| title_full_unstemmed | Gastrointestinal carcinoid tumors Tumores carcinoides digestivos |
| title_short | Gastrointestinal carcinoid tumors Tumores carcinoides digestivos |
| title_sort | gastrointestinal carcinoid tumors tumores carcinoides digestivos |
| topic | Tumores carcinoides digestivos Tumores neuroendocrinos Síndrome carcinoide Gastrointestinal carcinoid tumors Neuroendocrine tumors Carcinoid syndrome |
| url | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082010000900004 |
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