Platelet lysate as a novel serum-free media supplement for the culture of equine bone marrow-derived mesenchymal stem cells

Platelet lysate as a novel serum-free media supplement for the culture of equine bone marrow-derived mesenchymal stem cells

Abstract Background Mesenchymal stem cells (MSCs) produced for clinical purposes rely on culture media containing fetal bovine serum (FBS) which is xenogeneic and has the potential to significantly alter the MSC phenotype, rendering these cells immunogenic. As a result of bovine-derived exogenous pr...

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Bibliographic Details
Main Authors: Maria C. Naskou, Scarlett M. Sumner, Anna Chocallo, Hannah Kemelmakher, Merrilee Thoresen, Ian Copland, Jacques Galipeau, John F. Peroni
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Stem Cell Research & Therapy
Subjects:
Equine platelet apheresis
Equine platelet lysate
Mesenchymal stem cells
Fetal bovine serum
Cell culture
Online Access:http://link.springer.com/article/10.1186/s13287-018-0823-3

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