Comprehensive Analysis of HIV-1 Integrase Resistance-Related Mutations in African Countries

Comprehensive Analysis of HIV-1 Integrase Resistance-Related Mutations in African Countries

The growing emergence of non-nucleoside reverse transcriptase inhibitor (NNRTI) HIV drug resistance in sub-Saharan Africa (SSA) led to the World Health Organization (WHO) recommending, in 2018, a transition to dolutegravir (DTG) as a first-line antiretroviral therapy (ART) in SSA. The broad HIV-1 ge...

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Bibliographic Details
Main Authors: Francesco Branda, Marta Giovanetti, Leonardo Sernicola, Stefania Farcomeni, Massimo Ciccozzi, Alessandra Borsetti
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pathogens
Subjects:
HIV-1
integrase
drug resistance
viral evolution
African countries
Online Access:https://www.mdpi.com/2076-0817/13/2/102

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