Chordoma: retrospective analysis of 24 cases
INTRODUCTION: Chordoma is a rare and slow-growing tumor, with local aggressiveness and preferential localization in the vertebral column. OBJECTIVE: The main objective of this study is to evaluate natural history and results of treatment of chordomas. METHODOLOGY: This is a retrospective study from...
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| Format: | Article |
| Language: | English |
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Associação Paulista de Medicina
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| Series: | São Paulo Medical Journal |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801996000600006&lng=en&tlng=en |
| _version_ | 1811197995365957632 |
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| author | Ademar Lopes Benedito Mauro Rossi Claudio Regis Sampaio Silveira Antonio Correa Alves |
| author_facet | Ademar Lopes Benedito Mauro Rossi Claudio Regis Sampaio Silveira Antonio Correa Alves |
| author_sort | Ademar Lopes |
| collection | DOAJ |
| description | INTRODUCTION: Chordoma is a rare and slow-growing tumor, with local aggressiveness and preferential localization in the vertebral column. OBJECTIVE: The main objective of this study is to evaluate natural history and results of treatment of chordomas. METHODOLOGY: This is a retrospective study from 1953 to 1993. MATERIAL AND METHODS: The age ranged from 2 to 86 years (mean=34.5). Twelve patients were male and 12 female. The localization of the tumor was: 20 in the sacral region, 3 in head and neck and one out of the spine. RESULTS: The treatment, alone or combined, was surgery, radiation therapy and chemotherapy. The survival rate for patients with lesions in the sacrum ranged from 4 to 119 months, since the date of the symptoms. The 5-year overall survival was 4.2%. CONCLUSION: Chordoma is a rare and slow growing tumor, with a very difficult approach by surgery due to its preferential location in the sacrum and poor therapeutic results with radiation therapy or chemotherapy, mainly in patients with advanced disease. |
| first_indexed | 2024-04-12T01:23:45Z |
| format | Article |
| id | doaj.art-fcd7c9ca45a946bab61f476c440ba88f |
| institution | Directory Open Access Journal |
| issn | 1806-9460 |
| language | English |
| last_indexed | 2024-04-12T01:23:45Z |
| publisher | Associação Paulista de Medicina |
| record_format | Article |
| series | São Paulo Medical Journal |
| spelling | doaj.art-fcd7c9ca45a946bab61f476c440ba88f2022-12-22T03:53:43ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-946011461312131610.1590/S1516-31801996000600006S1516-31801996000600006Chordoma: retrospective analysis of 24 casesAdemar Lopes0Benedito Mauro Rossi1Claudio Regis Sampaio Silveira2Antonio Correa Alves3Hospital A. C. CamargoHospital A. C. CamargoHospital A. C. CamargoHospital A. C. CamargoINTRODUCTION: Chordoma is a rare and slow-growing tumor, with local aggressiveness and preferential localization in the vertebral column. OBJECTIVE: The main objective of this study is to evaluate natural history and results of treatment of chordomas. METHODOLOGY: This is a retrospective study from 1953 to 1993. MATERIAL AND METHODS: The age ranged from 2 to 86 years (mean=34.5). Twelve patients were male and 12 female. The localization of the tumor was: 20 in the sacral region, 3 in head and neck and one out of the spine. RESULTS: The treatment, alone or combined, was surgery, radiation therapy and chemotherapy. The survival rate for patients with lesions in the sacrum ranged from 4 to 119 months, since the date of the symptoms. The 5-year overall survival was 4.2%. CONCLUSION: Chordoma is a rare and slow growing tumor, with a very difficult approach by surgery due to its preferential location in the sacrum and poor therapeutic results with radiation therapy or chemotherapy, mainly in patients with advanced disease.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801996000600006&lng=en&tlng=enChordomasacral tumornotochordbone tumortreatment |
| spellingShingle | Ademar Lopes Benedito Mauro Rossi Claudio Regis Sampaio Silveira Antonio Correa Alves Chordoma: retrospective analysis of 24 cases São Paulo Medical Journal Chordoma sacral tumor notochord bone tumor treatment |
| title | Chordoma: retrospective analysis of 24 cases |
| title_full | Chordoma: retrospective analysis of 24 cases |
| title_fullStr | Chordoma: retrospective analysis of 24 cases |
| title_full_unstemmed | Chordoma: retrospective analysis of 24 cases |
| title_short | Chordoma: retrospective analysis of 24 cases |
| title_sort | chordoma retrospective analysis of 24 cases |
| topic | Chordoma sacral tumor notochord bone tumor treatment |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801996000600006&lng=en&tlng=en |
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