Plasmacytoid Dendritic Cells Are Largely Dispensable for the Pathogenesis of Experimental Inflammatory Bowel Disease

Plasmacytoid Dendritic Cells Are Largely Dispensable for the Pathogenesis of Experimental Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is a chronic inflammatory condition caused by an aberrant immune response to microbial components of the gastrointestinal tract. Plasmacytoid dendritic cells (pDCs) are innate immune cells specialized in the production of type I interferons and were recently implicat...

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Bibliographic Details
Main Authors: Catherine M. Sawai, Lee Serpas, Antonio Galvao Neto, Geunhyo Jang, Ali Rashidfarrokhi, Roland Kolbeck, Miguel A. Sanjuan, Boris Reizis, Vanja Sisirak
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
Plasmacytoid dendritic cell (PDC)
Interferon Type I
colitis
Inflammatory bowel disease (IBD)
autoimmune disease
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02475/full

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