Successful Management of Metastatic Lymph Nodes in the Chest by Laser Ablation via Endoscopic Ultrasound: A Case Report
Isolated spread of metastatic breast carcinoma to mediastinal lymph nodes is not an uncommon phenomenon. The prognosis worsens with the advent of any metastases in the chest. Conventional treatment mandates chemotherapy or radiotherapy as a control measures. Laser treatment has helped many patients...
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JCDR Research and Publications Private Limited
2024-01-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/18922/67665_CE[Ra1]_F[SK]_QC&REF(KK_IS)_PF1(AG_DK)_PFA(AG_KM)_PN(KM).pdf |
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| author | Rusy Bhalla Keyur Sheth Ravi Gupta |
| author_facet | Rusy Bhalla Keyur Sheth Ravi Gupta |
| author_sort | Rusy Bhalla |
| collection | DOAJ |
| description | Isolated spread of metastatic breast carcinoma to mediastinal lymph nodes is not an uncommon phenomenon. The prognosis worsens with the advent of any metastases in the chest. Conventional treatment mandates chemotherapy or radiotherapy as a control measures. Laser treatment has helped many patients with inaccessible or inoperable tumours, as it works on devascularisation and can benefit both benign and malignant tumours. This is a case report of a patient who did not respond to Trastuzumab and T-DM1 (Trastuzumab with Emtansine). She developed mediastinal lymph nodes during treatment with TDM1. Additionally, she had a documented change in hormonal status from Human Epidermal growth factor Receptor-2 (HER2) positive to negative. She underwent
laser ablation of mediastinal lymph nodes around the trachea. A Positron Emission Tomography (PET) scan after six months showed a total resolution of the lymph nodes with no significant uptake in the chest or any other part of the body. Laser ablation of mediastinal lymph nodes is a very skillful and demanding procedure that can be attempted in refractory and isolated cases where chemotherapy and radiation have failed. Further studies are needed to assess the long-term results of this new procedure. |
| first_indexed | 2024-03-08T15:45:25Z |
| format | Article |
| id | doaj.art-fcd9503ba31e4374b0bc6394d8085444 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-03-08T15:45:25Z |
| publishDate | 2024-01-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-fcd9503ba31e4374b0bc6394d80854442024-01-09T12:00:29ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2024-01-011801010310.7860/JCDR/2024/67665.18922Successful Management of Metastatic Lymph Nodes in the Chest by Laser Ablation via Endoscopic Ultrasound: A Case ReportRusy Bhalla0Keyur Sheth1Ravi Gupta2Consultant Laser Surgeon, Department of Oncology, Criticare Asia Hospital, Mumbai, Maharashtra, India.Gastroenterologist, Department of Oncology, Criticare Asia Hospital, Mumbai, Maharashtra, India.Consultant Interventional Gastroenterologist, Department of Oncology, Criticare Asia Hospital, Mumbai, Maharashtra, India.Isolated spread of metastatic breast carcinoma to mediastinal lymph nodes is not an uncommon phenomenon. The prognosis worsens with the advent of any metastases in the chest. Conventional treatment mandates chemotherapy or radiotherapy as a control measures. Laser treatment has helped many patients with inaccessible or inoperable tumours, as it works on devascularisation and can benefit both benign and malignant tumours. This is a case report of a patient who did not respond to Trastuzumab and T-DM1 (Trastuzumab with Emtansine). She developed mediastinal lymph nodes during treatment with TDM1. Additionally, she had a documented change in hormonal status from Human Epidermal growth factor Receptor-2 (HER2) positive to negative. She underwent laser ablation of mediastinal lymph nodes around the trachea. A Positron Emission Tomography (PET) scan after six months showed a total resolution of the lymph nodes with no significant uptake in the chest or any other part of the body. Laser ablation of mediastinal lymph nodes is a very skillful and demanding procedure that can be attempted in refractory and isolated cases where chemotherapy and radiation have failed. Further studies are needed to assess the long-term results of this new procedure.https://www.jcdr.net/articles/PDF/18922/67665_CE[Ra1]_F[SK]_QC&REF(KK_IS)_PF1(AG_DK)_PFA(AG_KM)_PN(KM).pdfinterventional endoscopic ultrasoundmediastinal lymph nodestrastuzumab |
| spellingShingle | Rusy Bhalla Keyur Sheth Ravi Gupta Successful Management of Metastatic Lymph Nodes in the Chest by Laser Ablation via Endoscopic Ultrasound: A Case Report Journal of Clinical and Diagnostic Research interventional endoscopic ultrasound mediastinal lymph nodes trastuzumab |
| title | Successful Management of Metastatic Lymph Nodes in the Chest by Laser Ablation via Endoscopic Ultrasound: A Case Report |
| title_full | Successful Management of Metastatic Lymph Nodes in the Chest by Laser Ablation via Endoscopic Ultrasound: A Case Report |
| title_fullStr | Successful Management of Metastatic Lymph Nodes in the Chest by Laser Ablation via Endoscopic Ultrasound: A Case Report |
| title_full_unstemmed | Successful Management of Metastatic Lymph Nodes in the Chest by Laser Ablation via Endoscopic Ultrasound: A Case Report |
| title_short | Successful Management of Metastatic Lymph Nodes in the Chest by Laser Ablation via Endoscopic Ultrasound: A Case Report |
| title_sort | successful management of metastatic lymph nodes in the chest by laser ablation via endoscopic ultrasound a case report |
| topic | interventional endoscopic ultrasound mediastinal lymph nodes trastuzumab |
| url | https://www.jcdr.net/articles/PDF/18922/67665_CE[Ra1]_F[SK]_QC&REF(KK_IS)_PF1(AG_DK)_PFA(AG_KM)_PN(KM).pdf |
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