Hysterectomy as a part of cardiovascular continuum
Aim. To study the stages of metabolic disorder progression after hysterectomy (HE). Material and methods. In total, 104 women (mean age 44,0±2,1 years) after supravaginal hysterectomy with intact ovaries were examined. The participants were divided into three main subgroups, according to the time si...
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Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2010-06-01
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Series: | Кардиоваскулярная терапия и профилактика |
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Online Access: | https://cardiovascular.elpub.ru/jour/article/view/2089 |
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author | V. I. Podzolkov A. E. Bragina T. I. Nikitina N. M. Podzolkova |
author_facet | V. I. Podzolkov A. E. Bragina T. I. Nikitina N. M. Podzolkova |
author_sort | V. I. Podzolkov |
collection | DOAJ |
description | Aim. To study the stages of metabolic disorder progression after hysterectomy (HE). Material and methods. In total, 104 women (mean age 44,0±2,1 years) after supravaginal hysterectomy with intact ovaries were examined. The participants were divided into three main subgroups, according to the time since HE (1 year, 3 years, and 5 years). The comparison group (CG) included 25 women (mean age 43,0±1,6 years). The levels of blood pressure (BP), blood lipid profile, immuno-reactive insulin (IRI) and C-peptide in plasma (fasting level and the level after oral glucose tolerance test) were measured. Results. Longer time since HE was associated with a significant increase in body mass index, systolic and diastolic BP, basal and stimulated C-peptide levels, basal and stimulated ITI levels, as well as in total cholesterol (CH) and low-density lipoprotein CH, comparing to the CG. There parameters were significantly and directly correlated with the time since HE. Conclusion. Metabolic disturbances were more pronounced in patients with longer time since HE. This allowed to specify the stages of post-HE metabolic syndrome and to justify the strategy for post-HE patients’ management. |
first_indexed | 2024-04-10T03:39:00Z |
format | Article |
id | doaj.art-fcd994b10c144160a8f5fe5b63bf252b |
institution | Directory Open Access Journal |
issn | 1728-8800 2619-0125 |
language | Russian |
last_indexed | 2024-04-10T03:39:00Z |
publishDate | 2010-06-01 |
publisher | «SILICEA-POLIGRAF» LLC |
record_format | Article |
series | Кардиоваскулярная терапия и профилактика |
spelling | doaj.art-fcd994b10c144160a8f5fe5b63bf252b2023-03-13T07:23:18Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252010-06-019373791800Hysterectomy as a part of cardiovascular continuumV. I. Podzolkov0A. E. Bragina1T. I. Nikitina2N. M. Podzolkova3ГОУ ВПО Московская медицинская академия им. И.М.СеченоваГОУ ВПО Московская медицинская академия им. И.М.СеченоваГОУ ДПО Российская медицинская академия последипломного образования. МоскваГОУ ДПО Российская медицинская академия последипломного образования. МоскваAim. To study the stages of metabolic disorder progression after hysterectomy (HE). Material and methods. In total, 104 women (mean age 44,0±2,1 years) after supravaginal hysterectomy with intact ovaries were examined. The participants were divided into three main subgroups, according to the time since HE (1 year, 3 years, and 5 years). The comparison group (CG) included 25 women (mean age 43,0±1,6 years). The levels of blood pressure (BP), blood lipid profile, immuno-reactive insulin (IRI) and C-peptide in plasma (fasting level and the level after oral glucose tolerance test) were measured. Results. Longer time since HE was associated with a significant increase in body mass index, systolic and diastolic BP, basal and stimulated C-peptide levels, basal and stimulated ITI levels, as well as in total cholesterol (CH) and low-density lipoprotein CH, comparing to the CG. There parameters were significantly and directly correlated with the time since HE. Conclusion. Metabolic disturbances were more pronounced in patients with longer time since HE. This allowed to specify the stages of post-HE metabolic syndrome and to justify the strategy for post-HE patients’ management.https://cardiovascular.elpub.ru/jour/article/view/2089постгистерэктомический синдромхирургическая менопаузаметаболический синдромдислипидемияартериальная гипертензияс-пептид |
spellingShingle | V. I. Podzolkov A. E. Bragina T. I. Nikitina N. M. Podzolkova Hysterectomy as a part of cardiovascular continuum Кардиоваскулярная терапия и профилактика постгистерэктомический синдром хирургическая менопауза метаболический синдром дислипидемия артериальная гипертензия с-пептид |
title | Hysterectomy as a part of cardiovascular continuum |
title_full | Hysterectomy as a part of cardiovascular continuum |
title_fullStr | Hysterectomy as a part of cardiovascular continuum |
title_full_unstemmed | Hysterectomy as a part of cardiovascular continuum |
title_short | Hysterectomy as a part of cardiovascular continuum |
title_sort | hysterectomy as a part of cardiovascular continuum |
topic | постгистерэктомический синдром хирургическая менопауза метаболический синдром дислипидемия артериальная гипертензия с-пептид |
url | https://cardiovascular.elpub.ru/jour/article/view/2089 |
work_keys_str_mv | AT vipodzolkov hysterectomyasapartofcardiovascularcontinuum AT aebragina hysterectomyasapartofcardiovascularcontinuum AT tinikitina hysterectomyasapartofcardiovascularcontinuum AT nmpodzolkova hysterectomyasapartofcardiovascularcontinuum |