Hysterectomy as a part of cardiovascular continuum

Aim. To study the stages of metabolic disorder progression after hysterectomy (HE). Material and methods. In total, 104 women (mean age 44,0±2,1 years) after supravaginal hysterectomy with intact ovaries were examined. The participants were divided into three main subgroups, according to the time si...

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Main Authors: V. I. Podzolkov, A. E. Bragina, T. I. Nikitina, N. M. Podzolkova
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2010-06-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/2089
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author V. I. Podzolkov
A. E. Bragina
T. I. Nikitina
N. M. Podzolkova
author_facet V. I. Podzolkov
A. E. Bragina
T. I. Nikitina
N. M. Podzolkova
author_sort V. I. Podzolkov
collection DOAJ
description Aim. To study the stages of metabolic disorder progression after hysterectomy (HE). Material and methods. In total, 104 women (mean age 44,0±2,1 years) after supravaginal hysterectomy with intact ovaries were examined. The participants were divided into three main subgroups, according to the time since HE (1 year, 3 years, and 5 years). The comparison group (CG) included 25 women (mean age 43,0±1,6 years). The levels of blood pressure (BP), blood lipid profile, immuno-reactive insulin (IRI) and C-peptide in plasma (fasting level and the level after oral glucose tolerance test) were measured. Results. Longer time since HE was associated with a significant increase in body mass index, systolic and diastolic BP, basal and stimulated C-peptide levels, basal and stimulated ITI levels, as well as in total cholesterol (CH) and low-density lipoprotein CH, comparing to the CG. There parameters were significantly and directly correlated with the time since HE. Conclusion. Metabolic disturbances were more pronounced in patients with longer time since HE. This allowed to specify the stages of post-HE metabolic syndrome and to justify the strategy for post-HE patients’ management.
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spelling doaj.art-fcd994b10c144160a8f5fe5b63bf252b2023-03-13T07:23:18Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252010-06-019373791800Hysterectomy as a part of cardiovascular continuumV. I. Podzolkov0A. E. Bragina1T. I. Nikitina2N. M. Podzolkova3ГОУ ВПО Московская медицинская академия им. И.М.СеченоваГОУ ВПО Московская медицинская академия им. И.М.СеченоваГОУ ДПО Российская медицинская академия последипломного образования. МоскваГОУ ДПО Российская медицинская академия последипломного образования. МоскваAim. To study the stages of metabolic disorder progression after hysterectomy (HE). Material and methods. In total, 104 women (mean age 44,0±2,1 years) after supravaginal hysterectomy with intact ovaries were examined. The participants were divided into three main subgroups, according to the time since HE (1 year, 3 years, and 5 years). The comparison group (CG) included 25 women (mean age 43,0±1,6 years). The levels of blood pressure (BP), blood lipid profile, immuno-reactive insulin (IRI) and C-peptide in plasma (fasting level and the level after oral glucose tolerance test) were measured. Results. Longer time since HE was associated with a significant increase in body mass index, systolic and diastolic BP, basal and stimulated C-peptide levels, basal and stimulated ITI levels, as well as in total cholesterol (CH) and low-density lipoprotein CH, comparing to the CG. There parameters were significantly and directly correlated with the time since HE. Conclusion. Metabolic disturbances were more pronounced in patients with longer time since HE. This allowed to specify the stages of post-HE metabolic syndrome and to justify the strategy for post-HE patients’ management.https://cardiovascular.elpub.ru/jour/article/view/2089постгистерэктомический синдромхирургическая менопаузаметаболический синдромдислипидемияартериальная гипертензияс-пептид
spellingShingle V. I. Podzolkov
A. E. Bragina
T. I. Nikitina
N. M. Podzolkova
Hysterectomy as a part of cardiovascular continuum
Кардиоваскулярная терапия и профилактика
постгистерэктомический синдром
хирургическая менопауза
метаболический синдром
дислипидемия
артериальная гипертензия
с-пептид
title Hysterectomy as a part of cardiovascular continuum
title_full Hysterectomy as a part of cardiovascular continuum
title_fullStr Hysterectomy as a part of cardiovascular continuum
title_full_unstemmed Hysterectomy as a part of cardiovascular continuum
title_short Hysterectomy as a part of cardiovascular continuum
title_sort hysterectomy as a part of cardiovascular continuum
topic постгистерэктомический синдром
хирургическая менопауза
метаболический синдром
дислипидемия
артериальная гипертензия
с-пептид
url https://cardiovascular.elpub.ru/jour/article/view/2089
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AT tinikitina hysterectomyasapartofcardiovascularcontinuum
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