RNA-Binding Proteins: Splicing Factors and Disease

RNA-Binding Proteins: Splicing Factors and Disease

Pre-mRNA splicing is mediated by interactions of the Core Spliceosome and an array of accessory RNA binding proteins with cis-sequence elements. Splicing is a major regulatory component in higher eukaryotes. Disruptions in splicing are a major contributor to human disease. One in three hereditary di...

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Bibliographic Details
Main Authors:	Alger M. Fredericks, Kamil J. Cygan, Brian A. Brown, William G. Fairbrother
Format:	Article
Language:	English
Published:	MDPI AG 2015-05-01
Series:	Biomolecules
Subjects:	RNA-binding proteins motif splicing
Online Access:	http://www.mdpi.com/2218-273X/5/2/893

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