A comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates.

Microglial cells are brain-specific macrophages that swiftly react to disruptive events in the brain. Microglial activation leads to specific modifications, including proliferation, morphological changes, migration to the site of insult, and changes in gene expression profiles. A change in inflammat...

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Bibliographic Details
Main Authors: Danish M Anwer, Francesco Gubinelli, Yunus A Kurt, Livija Sarauskyte, Febe Jacobs, Chiara Venuti, Ivette M Sandoval, Yiyi Yang, Jennifer Stancati, Martina Mazzocchi, Edoardo Brandi, Gerard O'Keeffe, Kathy Steece-Collier, Jia-Yi Li, Tomas Deierborg, Fredric P Manfredsson, Marcus Davidsson, Andreas Heuer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0284480